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Neuroscience 2 > Kruse Pharm Lect Biotransformation, Pharmacogenomics, Clinical Trials > Flashcards

Kruse Pharm Lect Biotransformation, Pharmacogenomics, Clinical Trials Flashcards

1
Q

CYP2A6? Polymorphism?

A

Nictoine and Coumarin; both

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2
Q

CYP2D6? polymorphism?

A

Codeine; Both

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3
Q

CYP3A4? Polymorphism?

A

all the things; only slow?

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4
Q

CYP2C9? Polymorphism?

A

Warfarin/Coumadin; only slow metabolizers- extra bleeding and bruising

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5
Q

CYP2C19

A

Clopidogrel

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6
Q

Warfarin is also effected by what enzyme?

A

Vitamin epoxide reductase complex 1 (VROC1)

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7
Q

CYP1A2? Polymorphism?

A

Caffeine; both slow and fast

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Neuroscience 2 (9 decks)

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