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Psych and Behavior > Segars ADHD Medications:Stimulants and Non-Stimulants > Flashcards

Segars ADHD Medications:Stimulants and Non-Stimulants Flashcards

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1
Q

ADHD occurs because of dysregulation of the______

A

prefrontal cortex

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2
Q

stimulants do what?

A

enhance neurotransmitter transmission by serving as direct and indirect noncatecholamine sympathomimetics

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3
Q
  • Amphetamine (ODT)
  • Dextroamphetamine
  • Lisdexamfetamine
  • Mixed Amphetamine salts (adderall)
A

Stimulants Amphetamines

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4
Q

What form of Methylphenidate comes in oral solution and a chewable tablet?

A

Methylin

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5
Q

What form of Methylphenidate comes in a patch?

A

Daytrana

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6
Q

How do you take:
Quillivant?
QuilliChew?

A
  • oral suspension

- Chewable tablet

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7
Q

All stimulants are controlled substances which means what?

A

1 month supply only, no refills, no samples

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8
Q

Stimulants: Non-IR Forms

Adzenys XR-ODT. What is the ratio IR and XR?

how do you take it?

At what age can you start taking this?

A

50% IR/ 50 XR%

take it orally

ages 6 and older

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9
Q

Stimulants: Non-IR Forms

Dyanavel XR Liquid. What is the IR/XR ratio?

How do you take it?

At what age can you start?

A

IR/XR not given

taken in a liquid form. GOOD FOR PATIENTS THAT CANT SWALLOW

ages 6 and older

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10
Q

Stimulants: Non-IR Forms

Dexedrine Spansules(dextroamphetamine). What is the ratio?

How do you take it?

At what age and who uses it?

A

IR/XR not given

capsules

ages 6 and older as well as Narcoleptic adults

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11
Q

Stimulants: Non-IR Forms

Vyvanse (lisdexamfetamine, prodrug of dextroamphetamine)

how do you take it?

Who takes it?

A

-He wants us to know that it is a pro drug and an amphetamine stimulant product

chewable pills in the works

-binge eating adults

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12
Q

Stimulants: Non-IR Forms

Adderall XR (amphetamine/dextroamphetamine)

Whats the ratio?
what age group/who takes it?

A

50% IR/ 50% XR

kids ages 3 and up
Narcoleptic adults

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13
Q

Stimulants:Non-IR Forms

Concerta (methylphenidate). what is the ratio?

how do you take it?

how old to take?

A

22% IR/ 78% XR

capsule

ages 6 and up

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14
Q

Stimulants:Non-IR Forms

Ritalin LA (methylphenidate). whats the ratio?

how do you take it?

what age?

A

50% IR/ 50% LA

Capsule

Ages 6 and up

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15
Q

Stimulants: Non-IR Forms

Metadate CD (methylphenidate). whats the ratio?
how do you take it?

what ages?

A

30% IR/ 70% CD

capsule

ages 6 and up

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16
Q

Stimulants: Non-IR Forms

Aptensio XR (methylphenidate). Whats the ratio?

how do you take it?

what ages?

A

40% IR/ 60% XR

capsule

ages 6 and up

17
Q

Stimulants: Non-IR Forms

Daytrana (patch) (methylphenidate).

how do you take it?
how long do you wear it?
how long does it work?

Age?

A

patch
wear for 9 hours and it works for 10-12 hours
Ages 6 and up

18
Q

Stimulants:Non-IR Forms

QuilliChew ER (methylphenidate). what is the ratio?

what is unique for this drug?

age group?

A

30% IR/ 70% ER

is the only extended-release chewable methylphenidate tablet

ages 6 and up

19
Q

Stimulants:Non-IR Forms

Quillivant XR (Methylphenidate). What is the ratio?

what is unique for this drug?

age group?

A

20% IR/ 80% XR

only extended-release oral methylphenidate suspension

ages 6 and up

20
Q

Stimulants: Non-IR Forms

Focalin XR (dexmethylphenidate). what is the ratio?

A

50% IR/ 50% XR

21
Q

Rare side effects of stimulants?

A

sudden cardiac death

always asses for abnormalities first

22
Q

DO you need to worry about abuse in kids/teens?

A

no

23
Q

How do Non-Stimulants for ADHD work?

A

enhance NT transmission by:

  • inhibition of NE presynaptic uptake (atomoxetine)
  • agonists of CNS adrenergic receptors (gaunfacine/clonidine)
24
Q

Atomoxetine MOA

A
  • non-stimulant
  • is a singular acting agent not dual like the amphetamines are
  • inhibition of NE pre-synaptic reuptake
25
Q

Gaunfacine/Clonidine MOA

A

-non-stimulants

a2 agonists of CNS adrenergic receptors

26
Q

how long until non-stimulants work?

A

1-4 weeks +

27
Q

Different side effects of Atomoxetine compared to stimulants

A

-has no motor/vocal tics or seizures

+ suicidal ideations. liver injury and jaundice

28
Q

Be cautious of ______ when using atomoxetine

A

MOAIs

CYP2D6 inhibitors

29
Q

How must you take patients off Gaunfacine/Clonidine?

A

downward titration over 1+ weeks

30
Q
  • Adzenys
  • Dyanavel
  • Dexedrine Spansules
  • Vyvanse (lisdexamfetamine; pro-drug of dextroamphetamine)
  • Adderall
A

Amphetamines Stimulants

31
Q
  • Concerta
  • Ritalin
  • Metadate
  • Aptensio
  • Daytrana
  • QuilliChew
  • Quillivant
  • Focalin
A

Methylphenidates Stimulants

32
Q

Legal differences between stimulants and non-stimulants?

A
  • stimulants dont have samples. start RX month by month. eventually can give a max RX for 3 months
  • non-Stimulants don’t have any of those hang ups
33
Q

Atomoxetine

Guanfacine/Clonidine

A

Non-stimulants

Psych and Behavior (10 decks)

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