SEE 6

Question 1

cleomyocin is toxic to the?

Answer 1

lungs

Question 2

cisplatin is toxic to the ?

Answer 2

kidneys

Question 3

doxorubicin is toxic to the ?

Answer 3

heart

Question 4

cyclophophains is toxic to the ?

Answer 4

liver

Question 5

streptozocin is toxic to the ?

Answer 5

liver

Question 6

methotrexate is toxic to the?

Answer 6

liver

Question 7

where do CCB’s work?

Answer 7

phase 2, plateau phase of ventricular action potential & phase 4 of the pacemaker action potential

Question 8

what 3 things increase the likelihood of digitalis toxicity

Answer 8

hypokalemia, hypercalcemia, hypomagnesemia

Question 9

top 5 causes of anaphylactic reactions =

Answer 9

NMB, latex, abx, colloids, hypnotics.

Question 10

what is the universal recipient

Answer 10

AB

Question 11

what factors does cryoprecipitate contain

Answer 11

I, VIII, XIII

Question 12

whats the formula for ABL

Answer 12

EBV x (Hct - aHCT / HCT)

Question 13

whats the 4-2-1 rule

Answer 13

4ml/kg first 10kg, 2ml/kg second 10kg, 1ml/kg remainder….. shortcut is add 40 to total kg if >20

Question 14

too much LR causes what electrolyte disturbance

Answer 14

metabolic alkalosis

Question 15

mannitol causes ___volemia, ____kalemia, ___natremia

Answer 15

hypovolemia, hyperkalemia, hyponatremia

Question 16

virchows triangle -

Answer 16

endothelial injury, stasis or truant blood flow, hypercoagulability of blood

Question 17

hemophilia A = factor __ def

Answer 17

8

Question 18

hemophilia B = factor __ def

Answer 18

9 (christmas)

Question 19

what is the order of heat loss

Answer 19

radiation, convection, evaporation, conduction

Question 20

what are the 2 hormones of the posterior pit

Answer 20

adh and oxytocin

Question 21

which is more potent, T3 or T4?

Answer 21

T3 is 4x more potent

Question 22

T_ is converted to T_ in the tissues

Answer 22

T4 –> T3

Question 23

graves is ___ and hasimotos is ____

Answer 23

hyper, hypo

Question 24

thyroid storm occurs ___ posted

Answer 24

6-8h

Question 25

what are the cardiac effects of hypocalcemia

Answer 25

prolonged QT, dec myocardial contractility

Question 26

what is the formula for anion gap

Answer 26

na - cl - hco3

normal is 9-15

Question 27

ekg changes with hyperkalemnia

Answer 27

prolonged PR, widened QRS, peaked or tented T waves

Question 28

ekg changes of hypokalemia

Answer 28

prolonged PR and QT, flattened T wave, prominent U wave

Question 29

aldosterone causes sodium and water ___ and potassium and hydrogen ___

Answer 29

retention, excretion

Question 30

addisons dz means you have ____ aldosterone

Answer 30

dec. so hyponatremia and hyperkalemia

Question 31

cushings dz means you have

Answer 31

excessive cortisol. htn. hypokalemia, hyperglycemia. moon face, buff hump

Question 32

conn’s dz = primary _____ characterized by __Na and ___K

Answer 32

hyperaldosteronism, inc NA, dec K

Question 33

what is the best indicator of renal status

Answer 33

creatinine clearance

Question 34

whats the MOA Of diamox? hint it’s a carbonic anhydrase inhibitor

Answer 34

inhibits carbonic anhydrase in proximal tubule which decreases Na reabsorption

Question 35

___ your acids = alkalosis

Answer 35

puke

Question 36

___ your bases = acidosis

Answer 36

poop

Question 37

what is mendelsons

Answer 37

ph < 2.5, volume <25