Secretions of GI tract and pacreas Flashcards
what transporters are on lumen side of ductal cell
1) Na/ H exchanger
2) Cl/HCO3 exchanger
3) CFTR
4) H+/K+ exchanger
what transporters are on the basolateral side of ductal cell
1) Na/K ATpase
2) Cl channels
3) sodium bicarbonate co transporter
what are the parasympathetic pre and post synaptic nerves of the salivary glands
1) facial nerve
- submandibular gland
- sublingual gland
2) glossopharyngeal nerve
- parotid gland
what are the sympathetic pre and post synaptic nerves of the salivary glands
superior cervical ganglion
extend to glands in periarterial spaces
what does atropine do?
antagonist of mAChR
- decrease IP3 and Ca
- decrease saliva
how does aldosterone and ADH effect saliva comp?
decrease Na+ conc, increase K+ conc
omeprazole
- proton pump inhibitor
- inhibits H K ATPase in parietal cell
what cells are in pyloric gland?
G cells
what cells are in oxyntic gland?
parietal
chief cells
what transporters are on lumen side of parietal cell?
- H K ATPase
- cl channel
what transporters are on basolateral side of parietal cell?
- Na/K ATPase
- HCO3- Cl exhanger
what is the alkaline tide?
-when HCl is excreted by the parietal cell into the lumen, bicarbonate is absorbed into the blood
what phase of gastric HCL secretion does vagotomy abolish?
cephalic
sympathetic innervation to pancreas
-celiac and superior mesenteric plexus
parasympathetic innervation to pancreas
-vagus nerve
pre
