Secondary Hyperparathyroidism Flashcards
1
Q
Most common cause?
A
Chronic renal failure
2
Q
Symptoms? - 7
A
- Bone changes - calcium escapes
- Kidney stone forming (Nephrolithiasis)
- Polydypsia, Polyuria.
- Constipation, nausea, peptic ulcer, pancreatitis, bile stone
- Depression, seizures
- Weakness
- Calcification all over the body
3
Q
Bone pathophisiology
A
PTH activates RANKL and it binds to RANK receptor. activating Osteoclasts.
4
Q
What is ‘brown tumor?’
A
A fibrotic part of the bone created after fractures healing with fibrotic tissue.
Giant cells and hemosiderin laden macrophages.
5
Q
What is ‘von Recklinghausen disease’ ?
A
A more advanced stage bone disease, occurs after the bone underwent cystic changes called ‘Osteitis Fibrosa Cystica’
