Second Lecture Flashcards
Where does the sexual cycle occur in toxoplasmosis?
In cats and other felines.
In congenital toxoplasmosis, the infection localizes at first in what organs?
In the eye and the CNS.
What are the forms of disease that might arise in subjects infected with toxoplasmosis if they become immunosuppressed?
Exanthematous like typhus, lymphatic like glandular fever, cerebrospinal form like meningeoencephalitis, retinochoroiditis, myocarditis and pneumonia.
Why do IgM in fetus indicate active infection of toxoplasmosis?
Because maternal IgM cannot pass the placental barrier.
What’s Frenkel test? When is it positive?
It’s an intradermal test used to diagnose toxoplasmosis. It’s positive in both active and latent infections.
When’s Sabin Feldman dye test negative (failure to stain) in toxoplasmosis?
In positive cases, due to antigen antibody reaction.
What’s the treatment of toxoplasmosis?
Combination of pyrimethamine and sulfadiazine or trisulfapyrinidine.
Spiramycin.
What’s the role of the polar filaments in microsporidiosis?
It injects the sporoplasm inside the host cells which is the infective material.
What are the modes of infection in microsporidiosis?
Ingestion of spores, inhalation, ocular exposure, sexual contact.
What’s the commonest form of microsporidiosis?
Intestinal microsporidiosis
What are the treatments for microsporidiosis?
Albendazole for intestinal type, and topical fumagillin in ocular infection.
Define VLM.
Invasion of human tissues with the larvae of toxocara cati or toxocara canis, or rarely human ascaris, or strongyloides or ancylostoma.
What’s the infective stage and the mode of infection of VLM?
Embryonated egg of toxocara cati and canis. Ingestion of contaminated food and drinks.
What do the symptoms of VLM depend on?
On the site and number of eosinophilic granulomatous lesions.
Granulomatous endopthalmitis is a manifestation of..?
Visceral Larva Migrans
