Sec-2_Unit-5

Question 1

Formulation (mnemonic, constituents & egs)

Answer 1

AP State

Stabilisers(sugars, gelatin)
Preservatives(Thimerosal)
Adjuvants(Al salts)

Question 2

Regulatory approval of vaccine

Answer 2

CDSCO under DCGI

Question 3

Traditional vaccine methods(4)

Answer 3

LIST
Live-attenuated
Inactivated
Subunit
Toxoid

Question 4

Modern vaccine methods(4)

Answer 4

Recombinant DNA
Vector-based
mRNA
DNA

Question 5

Live attenuated vaccine egs

Answer 5

MMR
OPV(Oral Polio vaccine)

Question 6

Inactivated vaccine egs

Answer 6

IPV(Inactivated polio vaccine)
HepA
Rabies
Covaxin

Question 7

Subunit vaccine egs

Answer 7

HPV
Hep B
(same egs for Recom DNA vaccines)

Question 8

Toxoid vaccine egs

Answer 8

TT(Tetanus toxoid)
Diphtheria toxoid

Question 9

Vector based vaccine eg

Answer 9

Ebola vaccine

Question 10

mRNA vaccine egs

Answer 10

Pfizer-BioNTech COVID-19 vaccine
Moderna COVID-19 vaccine

Question 11

DNA vaccine eg

Answer 11

ZyCoV-D COVID-19 vaccine

Question 12

Pathogens cultured in DPT vaccine prep(toxoid)

Answer 12

Corynebacterium diphtheriae
Bordetella pertussis
Clostridium tetani

Question 13

In Rabies vaccine, Virus cultivation in a medium(2 methods)

Answer 13

cell-culture based(vero cells)
egg based(embryos of fertilised chicken eggs)

Question 14

Hepatis B vaccine prep antigen

Answer 14

HBsAg(Hep B surface Antigen)

Question 15

Purification in Hep, Rabies vaccine prep involves

Answer 15

Filtration
Centrifugation
Chromatography