Screening Flashcards

1
Q

What are the 3 ways of detecting disease?

A

Spontaneous presentation
Opportunistic case finding
Screening!!!!!!!!!!!!

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2
Q

What is the definition of screening?

A

A systematic attempt to detect an unrecognised condition via the application of tests and other procedures that are rapid and effective

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3
Q

What is the aim of screening?

A

IT IT NOT TO FIND SOMETHING EARLIER

It is to improve a patients outcomes compared to finding something the usual way

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4
Q

What are the 4 criteria for a screening program?

A
  1. CONDITION must be an important health issue: understood epidemiology, detectable early stage with cost effetive intervention
  2. TEST must be simple, safe, precise, valid and acceptable to patients
  3. TREATMENT must be effective and evidence based
  4. PROGRAMME should be based on high quality RCT evidence. It should be cost effective and be of positive benefit.
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5
Q

What are the current UK (NHS England) screening programmes? There are 11….

A
Diabetic retinopathy
Newborn and infant physical exam 
AAA
Bowel ca.
Breast screening
Cervical screening
Fetal abnormality
Infectious diseases in pregnancy
Newborn blood spot 
Newborn hearing
SCD and thalassaemia
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6
Q

What is sensitivity?

A

Proportion of actually diseased people who test +ve

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7
Q

What is specificity?

A

Proportion of actually healthy people who test -ve

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8
Q

What is PPV?

A

Probability that someone who tests +ve actually has the disease

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9
Q

What is NPV?

A

Probability that domino who tests -ve is actually healthy

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10
Q

What is lead time bias?

A

It may look like people are living longer, but in fact they die at the same time. They are just diagnosed earlier so appear to have had the disease for longer

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11
Q

What is length time bias?

A

Screening tends not to be used for aggressive diseases, so gives the false impression it it more useful than it is

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12
Q

What are some sociological critiques of screening?

A
Victim blaming
Individualising pathology
Mass surveillance
Morality
Most screening is targeted at women
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