Screening Flashcards
Types of screening based on population screened?
Mass
High risk
Multiphasic
Whole population screening called as ?
Mass screening
Level of prevention in prescriptive screening?
Secondary
Level of prevention in presumptive screening?
Primary level
What is screening time?
1st possible point of diagnosis to critical point of diagnosis
Lead time?
1st possible point of diagnosis to usual point of diagnosis
Good screening tool characteristics?
Long lead time
Short screening time
Characteristics of 1st possible point of diagnosis?
Highly interventional
Ideal
Expensive
Critical point of diagnosis characteristics?
Optimum
Affordable
Lead time bias?
Investigation with long lead time :
1. Virtual lowering of mortality rates
2. No changes in treatment outcome or absolute death rates
Criteria for good screening tool?
Affordable
Approachable/available
Acceptable
Valid, accurate, precise
Define validity, accuracy, precision?
Validity: Getting desired results within defined range
Accuracy: Closeness to true value
Precision: repeating/ reproductive of result
Define sensitivity and specificity?
Sensitivity: probability of having tested positive out of total diseased population
Specificity: probability of having tested negative out of total healthy population
Define false positive error rate and false negative error rate.
FPER: Tested positive out of healthy
FNER: TESTED NEGATIVE OUT OF Diseased POPULATION
Positive predictive values PPV?
Having disease out of tested positive
Negative predicted value NPV?
No disease out of tested negative population
False positive error rate formula?
FPER = 1-Specificity
False negative error rate formula?
FNER = 1-Sensitivity
Seriousness of error?
FP>FN or
T1>T2 or
Alpha> beta
False positive is related to and false negative is related to?
Type 1 and alpha errors in FP
Type 2 and beta errors in FN
Likelihood ratio ? + or -?
LR+ : Sn/(1-Sp)
LR- : (1-Sn)/Sp
Screening test vs diagnostic test requirements?
Screening: increased sensitivity & decreased false negative
Diagnostics: increased specificity & decreased false positive
Odds ratio?
No. Of times an event is likely to happen
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No. Of times an event is unlikely to happen