SCR - Anticoagulants SDCEP guidance Flashcards

1
Q

Give examples of DOACs.

A
  • apixaban
  • dabigatran
  • rivaroxaban
  • edoxaban
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2
Q

Give examples of vitamin K antagonists.

A

Warfarin

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3
Q

Give examples of antiplatelet drugs.

A
  • aspirin
  • clopidogrel
  • dipyridamole
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4
Q

What is considered a high bleeding risk procedure?

A
  • complex XLA (3+ or adjacent)
  • flap raising procedures
  • gingival recontouring
  • biopsy
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5
Q

What is considered a low bleeding risk procedure?

A
  • simple XLA (<3, not adjacent)
  • incision and drainage of swelling
  • 6PPC
  • subgingival PMPR
  • restorations with subgingival margins
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6
Q

What is considered a procedure with no bleeding risk?

A
  • LA
  • BPE
  • supragingival PMPR
  • restorations with supragingival margins
  • RCT
  • impressions
  • orthodontic appliances
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7
Q

Which DOACs are taken twice daily?

A
  • apxiaban
  • dabigatran
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8
Q

Which DOACs are taken once daily?

A
  • edoxaban
  • rivaroxaban
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9
Q

What is the guidance for a low risk procedure for a patient taking apixaban?

A

Treat without interrupting medication

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10
Q

What is the guidance for a low risk procedure for a patient taking dabigatran?

A

Treat without interrupting medication

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11
Q

What is the guidance for a low risk procedure for a patient taking edoxaban?

A

Treat without interrupting medication

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12
Q

What is the guidance for a high risk procedure for a patient taking apixaban?

A

Miss morning dose

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13
Q

What is the guidance for a high risk procedure for a patient taking dabigatran?

A

Miss morning dose

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14
Q

What is the guidance for a low risk procedure for a patient taking rivaroxaban?

A

Treat without interrupting medication

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15
Q

What is the guidance for a high risk procedure for a patient taking rivaroxaban?

A

Delay morning dose, wait until 4 hours after haemostasis achieved to take dose

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16
Q

What is the guidance for a high risk procedure for a patient taking edoxaban?

A

Delay morning dose, wait until 4 hours after haemostasis achieved to take dose

17
Q

When should the INR be checked?

A
  • <24 hours ideal
  • <72 hours if patient is stable
18
Q

What is the target range for the INR?

19
Q

What INR score indicates it is safe to treat patients?

20
Q

What is the advice for patients taking aspirin alone?

A

Treat without interrupting medication

21
Q

What is the advice for patients taking aspirin in combination with another antiplatelet?

A

Treat without interrupting medication

22
Q

What is the advice for patients taking clopidogrel?

A

Treat without interrupting medication

23
Q

What is the advice for patients taking dipyridamole?

A

Treat without interrupting medication

24
Q

What is the advice for patients taking antiplatelet and anticoagulant medication?

A

Consult prescribing clinician

25
What medical conditions are associated with increased bleeding risk?
- chronic renal failure - heart failure - liver disease - haematological malignancy - recent radio/chemotherapy - coagulation disorders - CTD
26
What is the mode of action of warfarin?
Vitamin K antagonist
27
What is the mode of action of apixaban?
Factor 10a inhibitor
28
What is the mode of action of edoxaban?
Factor 10a inhibitor
29
What is the mode of action of rivaroxaban?
Factor 10a inhibitor
30
What is the mode of action of dabigatran?
Direct thrombin inhibitor (factor 11a)
31
What is the mode of action of aspirin?
COX-I and COX-II inhibitor