Scleroderma Flashcards
1
Q
systemic sclerosis
A
autoimmune inflammatory condition affecting the skin
2
Q
types
A
limited
diffuse
3
Q
limited features
A
Calcinoisis Raymnaud's phenomenon Eosphageal problems Sclerodactyly Telangiectasia
tightening of skin limited to limbs, face and neck
4
Q
diffuse features
A
tightening of skin affecting anywhere
internal organs affected
+ CREST symptoms
5
Q
what respiratory problems occur
A
pulmonary hypertension
pulmonary fibrosis
6
Q
what organs can be affected
A
lungs
kidneys
7
Q
what are the antibodies
A
anti-centromere +ve - limited
anti-scl-70 - diffuse
8
Q
what is scleroderma
A
tightening and fibrosis of the skin without organ involvement
9
Q
management of systemic sclerosis
A
steroids, immunosuppressants
supportive management
