Antiphospholipid Syndrome Flashcards
1
Q
antiphospholipid syndrome
A
acquired disorder
2
Q
signs
A
venous/arterial thromboembolism
thrombocytopenia
fetal loss
prolonged APTT
3
Q
what antibodies will be seen
A
lupus coagulant
anti-cardiolipin
4
Q
management
A
Low dose aspirin
initial thrombotic event:
warfarin aiming for an INR of 2-3
recurring thrombotic event:
warfarin aiming for an INR of 3-4
5
Q
how it would be managed in pregnancy
A
initially aspirin
start low molecular weight heparin when foetal heart beat detected