Antiphospholipid Syndrome Flashcards

1
Q

antiphospholipid syndrome

A

acquired disorder

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2
Q

signs

A

venous/arterial thromboembolism
thrombocytopenia
fetal loss
prolonged APTT

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3
Q

what antibodies will be seen

A

lupus coagulant

anti-cardiolipin

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4
Q

management

A

Low dose aspirin
initial thrombotic event:
warfarin aiming for an INR of 2-3

recurring thrombotic event:
warfarin aiming for an INR of 3-4

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5
Q

how it would be managed in pregnancy

A

initially aspirin

start low molecular weight heparin when foetal heart beat detected

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