Scleritis Flashcards

1
Q

What is scleritis?

A

It is defined as a condition in which there is full-thickness inflammation of the sclera

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2
Q

What five risk factors are associated with scleritis?

A

Rheumatoid Arthritis

Systemic Lupus Erythematosus

Granulomatosis With Polyangiitis

Inflammatory Bowel Disease

Sarcoidosis

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3
Q

What is the main risk factor associated with scleritis?

A

Rheumatoid Arthritis

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4
Q

What are the seven clinical features of scleritis?

A

Severe Eye Pain

Eye Erythema

Eye Watering

Photophobia

Decreased Visual Acuity

Light Reflex Loss

Immobile Dilated Episcleral Vessels

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5
Q

Describe the eye pain associated with scleritis

A

It tends to be worse on movement

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6
Q

Describe the eye erythema associated with scleritis

A

It tends to be diffuse

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7
Q

What investigation is used to diagnose scleritis?

A

Phenylephrine Eye Drop Test

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8
Q

How is the phenylephrine eye drop test used to diagnose scleritis?

A

It is the investigation used to differentiate between scleritis and episcleritis

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9
Q

What is the mechanism of action of phenylephrine eye drops?

A

They blanch conjunctival and episcleral vessels - however not scleral vessels

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10
Q

What phenylephrine eye drop test reuslt indicates scleritis?

A

The eye erythema is unaffected

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11
Q

What is the most appropriate next step in suspected cases of scleritis?

A

Same-day ophthalmology referral

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12
Q

What are the three pharmacological management options of scleritis?

A

Oral NSAIDs

Oral Corticosteroids

Immunosuppressants

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13
Q

When are oral NSAIDs used to manage scleritis?

A

They are the first line pharmacological management option of mild to moderate scleritis

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14
Q

Name two NSAIDs used to manage scleritis

A

Ibuprofen

Naproxen

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15
Q

When are oral corticosteroids used to manage scleritis?

A

They are the first line pharmacological management option of severe scleritis

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16
Q

Name a corticosteroid used to manage scleritis

A

Prednisolone

17
Q

When are immunosuppressants used to manage scleritis?

A

They are recommended to manage resistant cases of scleritis

18
Q

Name an immunosuppressant used to manage scleritis

A

Methotrexate

19
Q

What are the six complications associated with scleritis?

A

Scleritis Perforation

Glaucoma

Cataracts

Uveitis

Retinal Detachment

Raised Intraocular Pressure

20
Q

What is the main complication associated with scleritis?

A

Scleritis Perforation

21
Q

What condition does scleritis present similarly to?

A

Episcleritis

22
Q

How do we differentiate between scleritis and episcleritis?

A

Scleritis = painful and injected vessels don’t mobilise when gentle pressure is applied on the sclera

Episcleritis = painless and injected vessels mobilise when gentle pressure is applied on the sclera