Schizosomiasis Flashcards

1
Q

Discuss life cycle of schistosomiasis/ bilharzia

A

Screenshot on phone

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2
Q

Outline clinical features of chronic phase of schistosomiasis

A

Fibrosis – bladder and ureters
Small bladder capacity
Ureteral strictures - hydronephrosis, hydroureter
Obstructive Nephropathy
Bladder Malignancy

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3
Q

Outline clinical features of early chronic phase of schistosomiasis

A

Ongoing reinfection and egg production
Ulceration and psuedopolyps –ureter and bladder
Lesions reversible with treatment before onset of fibrosis

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4
Q

How would you make a diagnosis of schistosomiasis

A

History – travel to endemic areas or
Blood count – Eosinophilia (hypersensitivity reaction)
Urine Microscopy
Bilharzia Antibody test
Cystoscopy and Biopsy
Ultrasonography
CT Intravenous Pyelogram

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5
Q

What treatment is used to eradicate worms in schistosomiasis

A

Worm eradication – Praziquantel 40mg/kg single dose or two divided dose.

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6
Q

What do you use to treat acute schistosomiasis syndrome (swimmers itch)

A

Corticosteroids

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7
Q

Which STI can be seen with Urethritis, clear or white discharge, Epididymitis, Prostatitis

A

Chlamydia trachomatis

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8
Q

What drugs or medication is used for nocturnal enuresis

A

Desmopressin (fluid restriction avoids Hyponatremia)
Imipramine/ Tofranil (TCA, s/e of cardiac arrhythmias)
Anticholinergic (if daytime sx)

(Nor before 7 years)

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9
Q

Which enuresis medication can lead to cardiac arrhythmias

A

Imipramine / Tofranil (TCA)

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10
Q

Which enuresis medication can cause Hyponatremia

A

Desmopressin

(Fluid restrict them)

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11
Q

Which enuresis medication can be given If pt has daytime sx

A

Anticholinergics

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12
Q

Which enuresis medication has high relapse rate

A

Desmopressin

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13
Q

What is the gold standard investigation for pneumaturia

A

CT with contrast

Others: Cystogram and Colonoscopy

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14
Q

In which patients is contrast contraindicated

A

Iodine allergy
Renal dysfunction

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15
Q

Hat are the indications for urodynamuc studies

A

LUTS in men
OAB
Dysfunctional voiding in children
Neuropathic bladder

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16
Q

What do urodynamic studies record or used to measure

A

They’re pressure measuring catheters placed in both bladder and rectum
Bladder filled with fluid then they pee
Measures
1. Pressure
2. Volume
3. Activity
4. Emptying of bladder

So filling, storage and voiding phases

17
Q

What are the risk factors for becteriuria in pregnancy (asymptomatic bacteriuria)

A

Low SES
Multi parity
Sickle cell trait

18
Q

Antibiotics of choice in pregnant patients for UTI prophylaxis

A

Penicillin (Amoxicillin) and Cephalosporins
Nitrofurantoin safe in 1st and 2nd Trimester - Not for G6PD deficiency
3-7 days

19
Q

Which antibiotics is contraindicated in pregnant patients with G6PD deficiency

A

Nitrofurantoin

20
Q

Which antibiotics are contraindicated in pregnant

A

Fluroquinolones
Bactrum
Erythromycin
Chloramphenicol