Schizophrenia Spectrum/ Other Psychotic Disorders

Question 1

Schizophrenia Dx

Answer 1

Active phase symptoms for at least 1 month with at least one symptom being delusions, hallucinations, or disorganized speech plus continuous signs of the disorder (e.g., odd behaviors and abolition) for at least six months that May include prodromal and/or residual phases.

Onset

Early teens to early 30s.
Male: early to mid 20s.
Female: late 20s.

Question 2

Schizophrenia Concordance Rate

Answer 2

Parent 6%
Biological sibling 9%
Child of one parent with sch 13%
Dizygotic twin 17%
Child of two parents with sch 46%
Monozygotic twin 48%

Question 3

Schizophrenia better prognosis

Answer 3

-Female gender
-Acute(sudden) and late onset of sx
-Comorbid mood sx

Question 4

Schizophrenia comorbid disorders

Answer 4

Anxiety Disorder
OCD
Tobacco Use Disorder

Question 5

Schizophrenia Brain Abnormalities

Answer 5

Enlarged ventricles
Hypofrontality

Positive sxs:dopamine hyperactivity in subcortical regions (striata’s areas).

Negative sxs: dopamine hypoactivity in cortical regions(prefrontal cortex).

Question 6

Schizophreniform Disorder DX

Answer 6

Two of five characteristic SX for at least one month but less than six months.
With at least one symptom being delusions, hallucinations, or disorganized speech.

Question 7

Schizophrenia 5 characteristic Sxs

Answer 7

Delusions
Hallucinations
Disorganized speech
Grossly disorganized or catatonic behavior
Negative symptoms ( avolition, alogia, anhedonia).

Question 8

Delusion

Answer 8

False belief based on incorrect inference about external reality that is firmly held despite obvious proof of the contrary.

Question 9

Illusion

Answer 9

Actual external stimulus is misperceived or misinterpreted.

Question 10

Schizophrenia linked neurotransmitters

Answer 10

Dopamine
Glutamate
Serotonin

Question 11

Schizoaffective

Answer 11

Concurrent sxs of schizophrenia and a major depressive or manic episode for most of the duration of the illness, but with the presence of delusions or hallucinations for two or more weeks without mood symptoms.

Question 12

Delusional Disorder

Answer 12

One or more delusions for at least one month and the overall functioning has not been markedly impaired.

Question 13

Brief Psychotic Disorder

Answer 13

One or more of four characteristics symptoms for at least one day but less than one month. One symptom being delusions, hallucinations, or disorganized speech.