schizophrenia spectrum

Question 1

ideas of refernece

Answer 1

belief that cues in external environment are related to individual

Question 2

delusions of control

Answer 2

thought broadcasiting and insertion

Question 3

somatic delusions

Answer 3

belief that one is infected with a disease or certain illness

Question 4

illusion

Answer 4

misinterpretation of existing sensory stimulus

Question 5

hallucination

Answer 5

sensory perception w/o external stimulus

Question 6

delusion

Answer 6

fixed false idiosyncratic belief

Question 7

duration criteria for schizophrenia

Answer 7

must have sx for at least 6 mo

Question 8

schizophrenia DSM5

Answer 8

2 or more of the following present for at least 1 month (at least one must be the first 3):
delusions
hallucinations
disorganized speech
catatonic behavior
negative sx

Question 9

duration for schizophreniform

Answer 9

1-6 mo

Question 10

duration criteria for brief psychotic disorder

Answer 10

<1 mo

Question 11

what causes neg sx in schizophrenia

Answer 11

inadequate dopaminergic activity in prefrontal cortex

Question 12

what causes positive sx in schizophrenia

Answer 12

excessive dopaminergic activity in mesolimbic cortex

Question 13

Neurotransmitter abnormalities in schizophrenia

Answer 13

inc dopamine
inc serotonin
inc NE
dec GABA
dec glutamate receptors

Question 14

Schizophrenia better prognostic factors

Answer 14

later onset
good social support
positive sx
mood sx
acute onset
female gender
few relapses
good premodbid functioning

Question 15

Schizophrenia worse prognostic factors

Answer 15

early onset
poor social support
negative sx
FH
gradual onset
male gender
many relapses
poor premorbid functioning
comorbid substance use

Question 16

Tx for schizophrenia

Answer 16

1st (D2 antag) or 2nd gen (D4>D3 antag and 5-HT2 antag) APS and behavioral therapy

Question 17

prognosis for pts with schizophreniform

Answer 17

1/3 recover completely and 2/3 progress to schizophrenia

Question 18

Tx for schizophreniform

Answer 18

hospitalize, 6 mo course of APS and supportive psychotherapy

Question 19

schizoaffective DSM5

Answer 19

meet MDD or manic criteria during which psychotic sx consistent with schizophrenia are also met

delusions or hallucinations for 2 weeks in absence of mood d/o sx

mood sx present for majority of psychotic illness

Question 20

tx for schizoaffective

Answer 20

hospitalize and supportive psychotherapy
2nd gen APS

mood stabilizers, antidepressants or ECT for mood sx

Question 21

risk of developing tardive dyskinesia w/ 1st gen APS

Answer 21

cumulative risk of 5% per yr

Question 22

brief psychotic d/o

Answer 22

psychotic sx as in schizophrenia

sx present from 1 day to 1 mo

rare dx (more rare then schizophrenia)

Question 23

brief psychotic d/o tx

Answer 23

hospitalize, supportive therapy, APS course for psychosis and benzos for agitation

Question 24

delusional d/o epidemiology

Answer 24

middle aged >40 yo

immigrants, hearing impaired, FH of schizophrenia

Question 25

delusional d/o duration criteria

Answer 25

delusions for at lest 1 mo

Question 26

delusional d/o DSM5

Answer 26

1+ delusions for at least 1 month

functioning in life is NOT significantly impaired and behavior is not obviously bizarre

Question 27

tx for delusional d/o

Answer 27

difficult to treat given the lack of insight and impairment

APS meds, supportive therapy, AVOID group therapy

Question 28

schizotypal

Answer 28

paranoid, odd or magical beliefs, eccentric, lack of friends, social anxiety

Question 29

schizoid

Answer 29

solitary activities, lack of enjoyment from social interactions, no psychosis