schizophrenia spectrum Flashcards
ideas of refernece
belief that cues in external environment are related to individual
delusions of control
thought broadcasiting and insertion
somatic delusions
belief that one is infected with a disease or certain illness
illusion
misinterpretation of existing sensory stimulus
hallucination
sensory perception w/o external stimulus
delusion
fixed false idiosyncratic belief
duration criteria for schizophrenia
must have sx for at least 6 mo
schizophrenia DSM5
2 or more of the following present for at least 1 month (at least one must be the first 3): delusions hallucinations disorganized speech catatonic behavior negative sx
duration for schizophreniform
1-6 mo
duration criteria for brief psychotic disorder
<1 mo
what causes neg sx in schizophrenia
inadequate dopaminergic activity in prefrontal cortex
what causes positive sx in schizophrenia
excessive dopaminergic activity in mesolimbic cortex
Neurotransmitter abnormalities in schizophrenia
inc dopamine inc serotonin inc NE dec GABA dec glutamate receptors
Schizophrenia better prognostic factors
later onset good social support positive sx mood sx acute onset female gender few relapses good premodbid functioning
Schizophrenia worse prognostic factors
early onset poor social support negative sx FH gradual onset male gender many relapses poor premorbid functioning comorbid substance use
Tx for schizophrenia
1st (D2 antag) or 2nd gen (D4>D3 antag and 5-HT2 antag) APS and behavioral therapy
prognosis for pts with schizophreniform
1/3 recover completely and 2/3 progress to schizophrenia
Tx for schizophreniform
hospitalize, 6 mo course of APS and supportive psychotherapy
schizoaffective DSM5
meet MDD or manic criteria during which psychotic sx consistent with schizophrenia are also met
delusions or hallucinations for 2 weeks in absence of mood d/o sx
mood sx present for majority of psychotic illness
tx for schizoaffective
hospitalize and supportive psychotherapy
2nd gen APS
mood stabilizers, antidepressants or ECT for mood sx
risk of developing tardive dyskinesia w/ 1st gen APS
cumulative risk of 5% per yr
brief psychotic d/o
psychotic sx as in schizophrenia
sx present from 1 day to 1 mo
rare dx (more rare then schizophrenia)
brief psychotic d/o tx
hospitalize, supportive therapy, APS course for psychosis and benzos for agitation
delusional d/o epidemiology
middle aged >40 yo
immigrants, hearing impaired, FH of schizophrenia
delusional d/o duration criteria
delusions for at lest 1 mo
delusional d/o DSM5
1+ delusions for at least 1 month
functioning in life is NOT significantly impaired and behavior is not obviously bizarre
tx for delusional d/o
difficult to treat given the lack of insight and impairment
APS meds, supportive therapy, AVOID group therapy
schizotypal
paranoid, odd or magical beliefs, eccentric, lack of friends, social anxiety
schizoid
solitary activities, lack of enjoyment from social interactions, no psychosis
