Good Sam Pimp Qs Flashcards
Psychotic
hallucination, delusion or thought d/o
delusion
fixed, false, idiosyncratic belief
hallucination
sensation/perception w/o stimulus
thought d/o
lack of connection btwn thoughts
What neuroleptic med is derived from clozapine
olanzapine
What study should you order before prescribing neuroleptics?
EKG (d/t risk of QTx prolongation → should be <450)
tardive dyskinesia
abrnml uncontrollable mvt of head, face and neck
when is pt at risk for tardive dyskinesia
after 3 mo on neuroleptic rx
what 2 neuroleptics are least likely to cause tardive dyskinesia and EPS
Quetiapine and Clozapine
Why is Quetiapine less likely to cause EPS?
less dopamine antagonism (targets other NTs)
What neuroleptic is associated with the most wt gain?
Olanzaline
2 BBW for all neuroleptics
higher risk of death in elderly, QTc prolongation
6 SE of clozapine
agranulocytosis, heart failure, tachycardia, seizures, higher risk of death in elderly, QTc prolonfation
How often do you check CBC for a pt on Clozapine
q wk for 1st 6 mo then q 2 wks for next 6 mo then q mo
Neuroleptic malignant syndrome
agitation/confusion, HTN, rigidity, ↑ CK, ↑ WBC
How do you distinguish NMS from serotonin syndrome
w/ lead pipe rigidity
3 criteria for depression
persistently low mood, persistently low mental/physical energy, persistently low self attitude
Best time to take sertaline
after breakfast
Which antidepressant is best for chronic neuropathic pain?
SNRI (duloxetine but caution in liver failure)
SNRI (venlafaxine) SE at high doses
HTN crisis
What is trazodone
mild antidepressant that is good for sleep induction
SE of trazodone
priapism
Low vs high dose mirtazapine
Low (<15 mg) targets histamine, indicated for insomnia
High (>15 mg) targets serotonin and NE receptors, indicated for depression
SSRI SE
hyponatremia (rare_
OCD
exposure is the cure, avoidance is the disease
Hallmark of OCD
sx are egodystonic (pt has good insight but x reporting is dec d/t shame)