Good Sam Pimp Qs Flashcards
Psychotic
hallucination, delusion or thought d/o
delusion
fixed, false, idiosyncratic belief
hallucination
sensation/perception w/o stimulus
thought d/o
lack of connection btwn thoughts
What neuroleptic med is derived from clozapine
olanzapine
What study should you order before prescribing neuroleptics?
EKG (d/t risk of QTx prolongation → should be <450)
tardive dyskinesia
abrnml uncontrollable mvt of head, face and neck
when is pt at risk for tardive dyskinesia
after 3 mo on neuroleptic rx
what 2 neuroleptics are least likely to cause tardive dyskinesia and EPS
Quetiapine and Clozapine
Why is Quetiapine less likely to cause EPS?
less dopamine antagonism (targets other NTs)
What neuroleptic is associated with the most wt gain?
Olanzaline
2 BBW for all neuroleptics
higher risk of death in elderly, QTc prolongation
6 SE of clozapine
agranulocytosis, heart failure, tachycardia, seizures, higher risk of death in elderly, QTc prolonfation
How often do you check CBC for a pt on Clozapine
q wk for 1st 6 mo then q 2 wks for next 6 mo then q mo
Neuroleptic malignant syndrome
agitation/confusion, HTN, rigidity, ↑ CK, ↑ WBC
How do you distinguish NMS from serotonin syndrome
w/ lead pipe rigidity
3 criteria for depression
persistently low mood, persistently low mental/physical energy, persistently low self attitude
Best time to take sertaline
after breakfast
Which antidepressant is best for chronic neuropathic pain?
SNRI (duloxetine but caution in liver failure)
SNRI (venlafaxine) SE at high doses
HTN crisis
What is trazodone
mild antidepressant that is good for sleep induction
SE of trazodone
priapism
Low vs high dose mirtazapine
Low (<15 mg) targets histamine, indicated for insomnia
High (>15 mg) targets serotonin and NE receptors, indicated for depression
SSRI SE
hyponatremia (rare_
OCD
exposure is the cure, avoidance is the disease
Hallmark of OCD
sx are egodystonic (pt has good insight but x reporting is dec d/t shame)
tx for OCD
exposure response prevention therapy + SSRI
5 sx of PTSD
exposure, intrusion sx, avoidance, behavior/mood changes, hyperarousal
tx for PTSD
CBT, SSRIs, prazosin (or clonidine)
2 SSRI that are FDA approved to treat PTSD
sertaline, paroxetine
off label use of gabapentin
anxiety
2 psych indications for propranolol
panic attacks, performance anxiety
SE of propranolol
agranulocytosis
3 tx for depressive episodes in bipolar d/o
quetiapine, olanzapine, lurasidone
unique SE of depakote (valproic acid
pancreatitis
2 indications for carbamezapine
epilepsy, bipolar d/o
SE of carbamezapine
agranulocytosis
diff btwn heroin and buprenorphine
buprenorphine is a partial mu agonist
heroin is a full agonist
danger of buprenorphine
precipitating withdrawal
3 benzos indicated for alc withdrawal and why
lorazepam, oxazepam, temazepam
metabolized via glucuronidation not via liver
how many calories qualifies as a binge
2000
most deadly psych d/o
anorexia
orthorexia
obsessing over eating foods that pt thinks are healthy
CXR shows cardiomegaly → what psych d/o should be on ddx
purging (specifically ipecac abuse - med that causes vomiting)
signs of purging on BMP
hypokalemia
↑ CO2
psych d/o on ddx of pt c/o ortho hypotension
eating d/o
what to watch w/ re-feeding syndrome
phosphate, potassium, and magnesium levels
HM biochem feature of refeeding syndrome
hypophosphataemia
tx for borderline personality d/o
dialectical behavorial tx
delirium
fluctulating levels of consciusness
consciousness
quality of mental life that varies on sepctrum from comatose to alert
dementia
progressive deterioration/impairment in global intellectual fn from previously established baseline level
greatest risk of falls in elderly
benzos
off label use of mirtazapine
nausea in elderly
best tx for hallucinations secondary to parkinson’s dz
quetiapine
first line tx for agitation sexondary to dementia
SSRI
first line tx for agitation secondary to delirium
non-pharm interventions (2nd line = trazodone)
when to treat dementia
when it interferes w/ IASLs
what is rivastigmine
acetylcholinesterase inhibitor (other is donepazil) indicated for dementia tx
Why is rivastigminr CI in pt on beta blockers
risk of bradycardia
how to differentiate Alzheimer’s from vascular dementia
vascular is stepwise, Alzheimer’s is progressive
Why not give elderly pts benzos
inc agitation, fall risk, cognitive decline
Reversible cause of dementia
hypothyprod, B12 or folate deficiency, syphilis (RPR screening, requires confirmation)
Which 2 anticonvulsants increase SI
lamotrigine, topiramate
which anticonvulsants cause weight loss
zonisamide
Capacity
ability to:
express/sustain a choice
understand relevant info
appreciate situation and consequences
manipulate info readily