Schizophrenia, etc Flashcards

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1
Q

What is the most common psychosis disorder?

A

schizophrenia

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2
Q

What are the 3 phases of schizophrenia?

A

prodromal
active
residual

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3
Q

What is the prodromal phase of schizophrenia like?

A

gradual change in behavior that may appear as personality or mood change lasting weeks to months

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4
Q

What is the active phase of schizophrenia like?

A

delusions, hallucinations, disorganized thinking and behavior
-can include agitation, sleeplessness, dangerous behavior

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5
Q

How long does the prodromal phase usually last?

A

weeks to months

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6
Q

What is the residual phase of schizophrenia like?

A

continuing oddities or thinking and behavior often the negative and cognitive symptoms

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7
Q

Are delusions and hallucinations usually present in the residual phase of schizophrenia?

A

not usually

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8
Q

What are cognitive symptoms? What are some examples?

A

subtle or dramatic deficits in higher intellectual or executive functions that impair adaptive function and decision
Ex: impaired focus and attention, marked deficits in working memory

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9
Q

When does schizophrenia generally begin to appear?

A

adolescence and young adults

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10
Q

During what phase are most patients treated for schizophrenia?

A

active phase

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11
Q

What are the two criteria required for schizophrenic diagnosis?

A
  1. active phase with prominent symptoms last > 1 month (unless interrupted by meds)
  2. a total duration of symptoms, regardless of phase lasts >6 mo
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12
Q

How do cytokines relate to the development of schizophrenia?

A

exposure to cytokines or infection in the 2nd trimester can be a risk factor

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13
Q

What happens to the frontal lobes to contribute to the development of schizophrenia?

A

decreased blood flow to the frontal lobes

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14
Q

Where does thinning in the brain occur, associated with schizophrenia?

A

medial temporal lobe cortex, frontal cortex, small anterior portions of the hippocampus

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15
Q

What characteristics do the ventricles of a schizophrenic patient have?

A

enlarged lateral and 3rd ventricles

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16
Q

What is delusional disorder?

A

circumscribed and often bizarre delusion in an otherwise normal-appearing patient

17
Q

How long must delusions of delusional disorder last for a diagnosis?

A

> 1 month

18
Q

What is the time frame of a brief psychotic disorder?

A

< 1 month

19
Q

What are some examples of positive symptoms?

A

behaviors not seen in normal people–> losing touch with reality:
–delusions, hallucinations, disordered thinking and speech

20
Q

What are negative symptoms?

A

disruptions in normal emotion and behavior.

  • harder to recognize than positive symptoms and can be mistaken for depression
  • -lack of pleasure, lack of ability to begin and sustain, neglect of personal hygiene
21
Q

How long must a patient have schizophrenic symptoms to be diagnosed?

A

6 months

22
Q

What neurotransmitters are know to be out of balance in schizophrenia? How is it abnormal?

A

dopamine is increased

23
Q

What part of the brain does dopamine effect (maybe) in schizophrenia causing positive symptoms?

A

mesolimbic system

24
Q

How does changes in dopamine cause negative symptoms in schizophrenia?

A

alteration of DA and hypofunction in the prefrontal cortex are thought to cause negative symptoms

25
Q

What is significant about using antipsychotics for schizophrenia in terms of symptoms?

A

Typical antipsychotics only treat positive symptoms

–Atypical antipsychotics can treat positive symptoms and also decrease some negative symptoms

26
Q

What is the difference between schizophrenia and schizophrenoform disorder?

A

length of symptoms: schizophrenoform disorder has same symptoms but last less than 6 months. schizophrenia has symptoms more than 6 months

27
Q

What would need to be proved to show psychosis to be a result of another medical condition?

A

No evidence that psychosis had occurred before the onset of the medical condition

28
Q

What is catatonia?

A

severe psychomotor disturbance that can be associated with many different disorders [schizophrenia being one]