Schizophrenia (antipsychotics)

Question 1

Chlorpromazine

Answer 1

Brand: Thorazine
Dosage: 10-200mg (BID-QID), MDD = 2g/day
Class: Typical antipsychotic
SEs: Orthostatic Hypo., drowsiness, xerostomia, N/V, constipation, urinary retention, blurred vision, photosensitivity, extrapyramidal S/Sx
Monitoring: Vitals, mental status, lipids, glucose, EPS severity, LFTs, involuntary movement, neuroleptic synd, CBCs
Drug Interactions: EtOH, CNS depressants, lithium, warfarin, other phenothiazine, propranolol, pindolol, divalproex, phenytoin, atropine
Other: IV + PO, PKU false positive, Preg C

Question 2

Fluphenazine

Answer 2

Brand: Prolixin
Dosage:
Class:
SEs:
Monitoring:
Drug Interactions:
Other:

Question 3

Perphenazine

Answer 3

Brand: Trilafon (generic only)
Dosage:
Class:
SEs: Orthostatic Hypo., drowsiness, xerostomia, N/V, constipation, urinary retention, blurred vision, photosensitivity, extrapyramidal S/Sx
Monitoring: Vitals, mental status, lipids, glucose, EPS severity, LFTs, involuntary movement, neuroleptic synd, CBCs
Drug Interactions:
Other:

Question 4

Trifluoperazine

Answer 4

Brand:
Dosage:
Class:
SEs: Orthostatic Hypo., drowsiness, xerostomia, N/V, constipation, urinary retention, blurred vision, photosensitivity, extrapyramidal S/Sx
Monitoring: Vitals, mental status, lipids, glucose, EPS severity, LFTs, involuntary movement, neuroleptic synd, CBCs
Drug Interactions:
Other:

Question 5

Prochlorperazine

Answer 5

Brand:
Dosage:
Class:
SEs: Orthostatic Hypo., drowsiness, xerostomia, N/V, constipation, urinary retention, blurred vision, photosensitivity, extrapyramidal S/Sx
Monitoring: Vitals, mental status, lipids, glucose, EPS severity, LFTs, involuntary movement, neuroleptic synd, CBCs
Drug Interactions:
Other:

Question 6

Thioridazine

Answer 6

Brand: Mellaril
Dosage:
Class:
SEs: Orthostatic Hypo., drowsiness, xerostomia, N/V, constipation, urinary retention, blurred vision, photosensitivity, extrapyramidal S/Sx
Monitoring: Vitals, mental status, lipids, glucose, EPS severity, LFTs, involuntary movement, neuroleptic synd, CBCs
Drug Interactions:
Other: