Schizophrenia and Psychotic Disorders Flashcards

1
Q

What is psychosis?

A

Represents an inability to distinguish between symptoms of delusion, hallucination and disordered thinking from reality.

Severe forms of mental illness.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How does psychosis present?

A

Hallucincations - have fun force and clarity of true perception. Located in external space with no external stimulus and they are not willed or controlled.
Can affect 5 special senses -auditory, visual, tactile, olfactory, gustatory.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is a delusion?

A

An unshakeable idea or belief which is not out of keeping with the person’s social and cultural background, it is held with extraordinary conviction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are some types of delusional belief?

A

Grandiose
Paranoid
Hypochondriacal
Self referential

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What illness are likely to have psychotic symptoms?

A

Schizophrenia
Delirium
Severe affective disorders e.g. depressive episode with psychotic symptoms.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is schizophrenia?

A

Severe mental illness affecting thinking, emotion and behaviour.

Most common cause of psychosis. M=F
Age of onset 15-35 years.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the symptoms of Schizophrenia?

A

Positive:
Hallucinations
Delusions
Disordered thinking

Negative:
Apathy
Lack of interest
Lack of emotions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

How does ICD-10 classify Schizophrenia?

A

For >1month in the absence of organic or affective disorder at leat 1 of the following:

Alienation of thought as thought echo, thought insertion to withdrawal or thought broadcasting.

Delusions of control, influence or passivity, clearly referred to the body or limb movement actions or sensations, delusional perception.

Hallucinatory voices giving a running commentary on the patients behaviour or discussing them between themselves, or other types of hallucinatiory voices coming from some part of body.

Persistent delusions of other kinds that are culturally inappropriate and completely impossible e.g. being able to control the weather.

And/or at least 2 of the following:

Persistent hallucinations in any modality occurring every day.

Neologisms, breaks or interpolations in the train of thought resulting in incoherent or irrelevant speech.

Catatonic behaviour such as excitement, posturing or waxy flexibility, negativism, mutism and stupor.

Negative symptoms such as marked apathy, paucity of speech and blunting or incongruity of emotional responses.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What needs to be considered in the aetiology of psychosis?

A

Biological factors
Psychological factors
Social factors
Evolutionary theories

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are some biological factors that may affect Schizophrenia?

A
Genetics
Neurochemistry - dopamine hypothesis, glutamate, GABA and serotoninergic transmission. 
Obstetric complications 
Maternal influenza
Winter birth
Substance misuse
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are some psychological theories of psychosis?

A

Jung’s concept of Collective unconsciousness (memory traces from man’s ancestral past)

Conrad using Gestalt psychology to identify stages in development of delusions.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are some social and psychosocial factors affecting schizophrenia?

A
Occupation
Social class
Migration
Social isolation
Life events
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is Delirium or Acute Organic Brain Syndrome?

A

Consequent upon brain or systemic disease.
Prominent visual experience, hallucinations and illusions.
Affect of terror.
Delusions are persecutory and evanescent.
Fluctuating worse at night.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the symptoms of a depressive affective psychosis?

A

Depressive episode with: Delusions of guilt, worthlessness and persecution.
Derogatory auditory hallucinations.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the symptoms of a manic affective psychosis?

A

Manic episode with:
Delusions of grandeur, special powers or messianic roles.
Gross overactivity, irritability and behavioural disturbance, manic excitement.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is Schizoaffective disorder?

A

Mix of affective and schizophrenia like features.

They occur at the same time.

17
Q

What is the treatment for schizophrenia?

A

Earlier treatment the better the outcome.
Anti-psychotics - think about side-effects when choosing.
Clozapine if number 1 for treatment resistant schizophrenia.

18
Q

What is the prognosis and recovery for Schizophrenia?

A

Early intervention and more effective treatment mean outcome is not as bleak as used to be.
Small group will have chronic symptoms and little recovery.

19
Q

What are some good prognostic factors for Schizophrenia?

A
Absence of family history
Good premorbid function - stable personality/relationships
Clear precipitant
Acute onset
Mood disturbance
Prompt treatment
Maintenance of initiative, motivation.
20
Q

What are some poor prognostic factors for Schizophrenia?

A

Slow, insidious onset and prominent negative symptoms.
Mortality is 1.6 times higher than general pop.
Linked to cardiovascular disease, respiratory disease and cancer.
Suicide risk is 9 times higher.
Death from violent incidents is twice as high.
36% of patient have a substance misuse problem.
Childhood onset.