Child and Adolescent Psychiatry Flashcards

1
Q

What are conduct disorders?

A

Characterised by repetitive and persistent patterns of antisocial, aggressive or defiant behaviours which violate age-appropriate social norms.

Associated with in increased risk of death often sudden or by violent means.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How is conduct disorder managed?

A

Multiagency communication.

Parent training programme
Modification of school environment 
Functional family therapy
Multi-systemic therapy
Child interventions - social skills, problem-solving, anger management, confidence building. 
Treat co-morbidities
Address child protection concerns.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are Hyperkinetic disorders?

A

Characterised by core features of developmental abnormal inattention, hyperactivity and impulsivity present across time and situations.

Highly co-morbid e.g. motor coordination problems, substance misuse etc.

Majority are symptomatic into adulthood, especially inattention.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the management options for ADHD?

A
Psychoeducation
Medication - stimulants, atomoxetine, guanfacine. 
Behavioural interventions e.g. realistic expectations, contingency management. 
Parent training
School interventions
Treat co-morbidity
Voluntary organisations
Benefits
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What medication is indicated for ADHD or ADD?

A
Methylphenidate. 
Acts on Nad and DA systems. 
taken orally.
Non-Addictive, purely symptomatic treatment that lasts 4 hours and then wears off. 
Atomoxetine is 2nd line.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the side effects of methylphenidate?

A

Decreased appetite
Weight loss
Trouble sleeping
BP is also affected a little.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are some factors that increase the risk of suicide?

A
Persistent suicidal ideas
Previous suicidal behaviour
High lethality of method used
High suicidal intent and motivation.
Ongoing precipitating stresses
Mental disorder
Poor physical health
Impulsivity, neuroticism, low self esteem, hopelessness
Parental psychopathology and suicidal behaviour
Physical/sexual abuse
Disconnection from support systems.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is involved in twin studies?

A

Comparison of DZ and MZ twins and calculates the % variance between them due to environment and genetics.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are some examples of intra-uterine and perinatal factors that affect psychological development?

A
Maternal health - antibodies, diabetes etc. 
Substance misuse
Toxins - lead, mercury, PCBs
Drugs - psychotropic/anti-epileptic drugs
Epigenetics
Endocrine environment 
Immune environment
Premature birth
Twinning
Impressive levels of resilience
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the features of foetal alcohol syndrome?

A

Growth retardation in Body, head, brain and eyes.

Multiple neuro-developmental effects such as sensorimotor, cognitive development, executive function and language.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How does White matter connectivity affect brain function?

A

Required for functions that need interplay between brain areas e.g working memory between hippocampus and anterior cingulate nucleus.

Low connectivity is associated with more neural noise, intra-individual variability and cognitive instability. Typically associate with ADHD.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How does early life influence stress response?

A

Influences function of limbic circuit including amygdala. Determines subsequent patterns of stress response such as withdrawal or aggressive response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is operant conditioning?

A

Type of associated learning where behaviour is modified through reward/reinforcement or punishment.

Dopamine neutrons fire when you associate an action with a subsequent reward.

Early adversity decreases the dopamine response.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the application of reward deficiency model also called?

A

Hypoactive reward response.

Addiction or increased delay-aversion.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is executive and cortical control?

A

Taking control over automatic and learned behaviours. Applied in CBT.
Inhibits prepotent responses.
Intentional decision making and forward planning but it requires self awareness and capacity to self-monitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is delay-aversion?

A

Inability to wait and maintain attention in the absence of immediate reward.

17
Q

What are some mental health problems associated with being out of school?

A
Anxiety
Conduct disorder
Autism
Depression
Obsessive compulsive disorder.
18
Q

What is separation anxiety?

A

Fear of leaving significant someone or place. Usually fear of leaving parents and the house to go to school.

19
Q

What are the features of anxiety disorders?

A

Anxious thoughts and feelings (impending doom).
Autonomic symptoms
Avoidant behaviour.

20
Q

How is the Amygdala affected in anxiety disorders?

A

Amygdala activity is surpassed by right ventrolateral amygdala when labelling emotions.
In generalised anxiety disorders there is reduced connectivity between right ventrolateral cortex and amygdala.

21
Q

What are the long term effects of successful behavioural treatment?

A

Challenge - Success - self confidence - resilience.

22
Q

What are the long-term effects of no behavioural treatment?

A

Challenge - avoidance - Low self confidence - Vulnerability.

23
Q

What is autism spectrum disorder?

A

Syndrome of distinctive behavioural abnormalities. Often associated with low IQ but not defined by it. Present across life span and different settings.
Highly heritable.
M>F 3:1.

24
Q

What are some pathways and proteins that are expected to be affected in Autism Spectrum Disorder?

A

Glutaminergic proteins
GABA
5-HTT (serotonin transporter)
NMDA and GRIK2 (glutamate receptor subunits).

25
Q

What is the range of the autistic spectrum?

A

Least severe is autism that inly effects on synaptic function. Individuals have normal IQ.
More severe is autism with learning difficulties. Effects on synaptic function, neural migration and brain development.

26
Q

What are some distinctive features of autism?

A

Reciprocal conversation
Expressing emotional concern
Non-verbal communication - declarative pointing, modulated eye-contact, other gestures, facial expression.
Repetitive behaviour such as mannerisms and stereotypies. Obsessions, preoccupations and interests.
Rigid and inflexible pattern of behaviour - routines, rituals, play.

27
Q

What are some clinical features of ASD?

A

Decreased: self-other perspective taking, sharing/divided attention, flexible learning, social understanding.

Increased: rigidity, sameness, fixed learning patterns, technical understanding.

Younger/lower IQ:
Joint attention/attention to others.
Emotional responses
Movements and actions.

Older/higher IQ:
Conversation
Empathy
Interests.

28
Q

What are some clinical problems in ASD?

A
Learning disabilities
Sleep disturbances
Eating disturbances
Hyperactivity
High levels of anxiety/depression
OCD
School avoidance
Aggression
Temper tantrums
Self-injury
Self-harm
Suicidal behaviour (6x more likely).
29
Q

What are some genetic causes of ASD?

A

Co-morbid with congenital or genetic disorders e.g. rubella, callosal genesis, Down’s syndrome, Fragile X, Tuberous sclerosis.
Broader phenotype in siblings and parents.

30
Q

What is the management for ASD?

A

Recognition, description and acknowledgement of disability.
Establishing needs
Appreciating can’t and won’t.
Decrease the demands to reduce stress and improve coping.
Psychopharmacology.

31
Q

What are the key features of Oppositional Defiant disorder?

A
Refusal to obey adults request
Often argues with adults
Often loses temper
Deliberately annoys people
Touchy or easily annoyedly others
Spiteful or vindictive
32
Q

What are some key features of ADHD?

A

Aggression is impulsive and may not even be a feature,
Poor cognitive control and ability to sustain a goal.
Often remorseful
Resistant to pure behavioural management.
Stronger genetic component than ODD.

33
Q

What is parent training?

A

Useful in hard to manage children treatment.
1-2hrs a week for 8-12 weeks.
Structured therapy that is informed by social-learning theory.
Focuses on positive reinforcement of desired behaviour and developing positive parent-child relationships.