Schizophrenia and psychotic disorders

Question 1

What is psychosis?

Answer 1

A condition where a person loses touch with reality, affecting thoughts, perceptions, and behavior.

Question 2

What are Schneider’s First-Rank Symptoms of Schizophrenia?

Answer 2

Auditory hallucinations, thought insertion/withdrawal/broadcasting, passivity phenomena, and delusions of reference.

Question 3

Name three negative symptoms of schizophrenia.

Answer 3

Avolition, Alogia, Anhedonia.

Question 4

What is the most common type of hallucination in schizophrenia?

Answer 4

Auditory hallucinations (often third-person or running commentary).

Question 5

What is the main neurotransmitter implicated in schizophrenia?

Answer 5

Dopamine (Hyperactivity in the mesolimbic pathway, hypoactivity in the mesocortical pathway).

Question 6

What is the first-line treatment for schizophrenia?

Answer 6

Atypical antipsychotics (e.g., Risperidone, Olanzapine, Quetiapine, Aripiprazole).

Question 7

What dopamine pathway is responsible for positive symptoms in schizophrenia?

Answer 7

The mesolimbic pathway (excess dopamine activity).

Question 8

Name three key side effects of antipsychotics.

Answer 8

Extrapyramidal symptoms, metabolic syndrome, hyperprolactinemia.

Question 9

What is Neuroleptic Malignant Syndrome (NMS)

Answer 9

A life-threatening reaction to antipsychotics with fever, rigidity, and autonomic instability.