Schizophrenia Flashcards

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1
Q

types of hallucinations & brain scans

A
  • Auditory: hearing voices
    • Brocas area most active during hallucination: responsible for speech production, suggests patients are just listening to their own thought but unable to distinct them from external
  • Olfactory: smelling things
  • Visual: see things
  • Tactile: (burning or tingling sensation)
  • Gustary (tasting lemons)
  • d
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2
Q

Other causes of psychosis

A
  • L-dopa: Parkinson’s medication produces symptoms relating to
  • Cocaine, meth, and psychedelics
  • Huntington’s disease (disease of nerves, cognitive and psychiatric symptoms)
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3
Q

Neurobiological Contributions to schizophrenia

A
  • Overfiring of dopamine neurons
    • drugs that increase dopamine produce schizophrenia-like symptoms
    • Drugs that decrease DA decrease symptoms
    • Multiple NT likely involved
  • Enlarged ventricles (holes) in brain:
  • Cerrebellum shrinking: movement control– catatonia
  • Thalamus: controls incoming information to brain
    • Takes longer for sensory info to reach brain
    • Deficits in top-down processing
  • Viral infections in pregnancy
    • Most born with schizophrenia during winter
    • flu viruses may impact brain development
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4
Q

Psychosocial contributions Schizophrenia

A
  • Family interactions: high expressed emotion
    • Critisism hostility toward individual; tendency to blame them for their symptoms
    • greater chance of relapse
  • Stress may activiate underlying vulnerability
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5
Q

Antipsychotic side effects

A
  • First gen
    • grogginess, restlessness, weight gain
    • Parkinsons-like effects (tremors)
    • Tardive dyskinesia: unvoluntary movement of lips
  • Second gen
    • Fewer side effects, less effective
  • Compliance is a problem
    • don’t like side effects financial burden, bad relationship with doctors
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6
Q

Psychosocial Treatments (not CBT)

A
  • Psychoeducation: increased awareness, less self stigma
  • Training to form better relationships and skills to function
  • Family therapy to help families support patient
  • Token economics for inpatients: reward adaptive behaviors
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7
Q

CBT

A
  • help patients see thoughts as thoughts not external stimuli
  • help examine the evidence against delusions
    • e.g. “i built a time machine to get away because everyone is out to get me” ask if anyone helped them build a time machine, if they say their neighbor, maybe it’s evidence that not everyone is out to get them
  • Modify beliefs about schizophrenia: what are some strengths?
  • Focus on emotional distress
  • Some improvement over medication alone
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8
Q

Management, prevention, and recovery

A
  • Illness management and recovery: work towards meaningful life even with symptoms
    • Realistic goal setting: don’t say voices will go away
    • Involve community if possible
  • Prevention
    • Identify at-risk children
    • Supportive environment
    • Treatment at prodromal phase social skills
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9
Q

Schizophreniform

A
  • Psychotic symptoms last 1-6 months
  • Functional before psychotic episode
  • Better prognosis than schizophrenia: remission more possible
  • 0.2% lifetime prevelance
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10
Q

Brief Psychotic

A
  • at least 1 symptom positive of schizophrenia
  • less than a month
  • individual returns to normal functioning
  • Usually caused by trauma or stress
  • usually mid-30s
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11
Q

Schizoaffective

A
  • Symptoms of schizophrenia + major mood episode (depressive or manic)
  • psychotic symptoms must occur outside of mood episode for at least two weeks (otherwise manic w psychotic symptoms)
  • Long term prognosis slightly better than schizophrenia
  • do not get better on their own usually
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12
Q

Delusional disorder

A
  • Presence of 1 or more delusions for at least a month
  • May specify the type of delusion (erotomanic, persecutory, grandeur)
  • Lacks other symptoms of schizophrenia
  • Very rare
  • 30-35 age of onset
  • More common in females (55%0
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13
Q

Catatonia

A
  • Unusual motor responses like immobility or agitation
    • Maintaining awkward pose for hours and resiting efforts to be moved
    • Waxy flexibility: person can be placed in position and maintain it for long time
    • Pacing back and force or wildly moving armand legs
    • Meaningless motor behaviors
    • Echolalia: Mimicking others speech or movement
  • Can be diagnosed alone or present in psychotic disorders
  • Severe and rare
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14
Q

Schizophrenia overview

A
  • Delusions and hallucinations
  • Disorganized speech and behavior
  • Problems in self-care and life functioning
  • Inappropriate emotions
  • Heterogeneous: many possible presentations
  • Affects 1% population
  • Emerges late teens or early 30s then individual deteriorates quickly
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15
Q

History of term schizophrenia and misunderstandings

A
  • schizophrenia = split mind
    • splitting from reality as well as various functions of mind (emotion occurs separately from thought)
    • Recognized heterogenity of disorder
  • Misunderstandings
    • Some confuse with DID but schizophrenics do not experience distinct identities
    • Overuse of term “schizophrenic” minimize struggles associated with the illness
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16
Q

Positive symptoms

A
  • Delusion: strongly held false belief despite evidence against
    • Could help individual deal with stress and/or make sense of the world
    • Can sometimes appear logical or convincing
    • 90% experience
    • Can be a few large ones or many smaller ones
  • Hallucinations
    • Auditory: hearing voices
    • Olfactory: smelling things
    • Visual: see things
    • Tactile: (burning or tingling sensation)
    • Gustary (tasting lemons)
  • Delusions and hallucinations often co-occur
17
Q

negative symptoms

A
  • Absence of characteristcs expected from “normal” people
    • Avolition: inability to take part in goal directed activities e.g. hygiene
    • Alogia: the absence of speech
    • Anhedonia: lack of pleasure/indifference
    • Affective flattening: little expressed emotion when expected
  • asociality
    • not interested in social interactions
    • breakdown in empathy
18
Q

Disorganized

A
  • Word salad
  • Loose associations: rapidly shift from topic to topic
  • Tangentially: go off on tangents e.g. “How was your day” “the park was really beautiful”
  • Neologisms: making up new words
  • Clanging: prioritizing rhythm over meaning e.g. well hell it’s well to tell
  • Innapropriate emotional affect: smiling when talking about killing oneself
19
Q

Course

A
  • Promdal phase: 85% experience
  • 1-2 years before serious symptoms
  • Less severe yet unusual symptoms
    • Magical thinking e.g. believe you have telepathy
    • Illusions
    • Isolation
    • Lack of interests or energy
  • Early intervention is critical
20
Q

Gender and SES

A
  • Gender: equal in men and women
  • SES: lower SES
    • Downward drift: symptoms of schizophrenia result in loss of job, homelessness etc