Schizophrenia Flashcards
What is the prevalence of schizophrenia?
What is the normal age range of onset in men and in women?
1%
Men - 18 to 25
Women - 25 - 35
What are the 3 biggest risk factors for schizophrenia?
Being male
Urban area
Immigration
Give 3 positive symptoms of schizophrenia
Delusions
Hallucinations
Formal thought disorder
Give 3 negative symptoms of schizophrenia
Anhedonia
Social withdrawal/socially inappropriate behaviour
Flattening of mood
What are the ICD-10 1st-rank symptoms of schizophrenia?
Delusions of thought control
3rd person auditory hallucinations
Persistent delusions of any kind, usually persecutory or religious
List some ICD-10 2nd-rank symptoms of schizophrenia
Hallucinations other than 3rd person auditory
Thought disorder
Catatonia
Negative symptoms
What constitutes ICD-10 diagnosis of schizophrenia?
At least 1 1st-rank symptom and 2+ 2nd-rank symptoms for at least a month
What would be your top differentials for schizophrenia and how would they differ from schizophrenia?
- Schizoaffective disorder - schizophrenia + affective symptoms in equal measure
- Schizotypal PD - no delusions/hallucinations
- Delusional disorder - delusions only
- Brief psychotic episode if under 1 month
- Drug-induced psychosis
What is the most common form of schizophrenia and what are its key features?
Paranoid schizophrenia - hallucinations and delusions
Outline the broad management plan for schizophrenia using a bio-pyscho-social model
- Antipsychotic - usually atypical - oral or IM depot
- Psychological intervention - CBT or family therapy
- Social support
What would you do if schizophrenia was not responding to treatment?
- Review diagnosis
- Check compliance with medications/engagement with psych therapies
- Consider Clozapine if 2 antipsychotics including one 2nd-generation used.
