Schizophrenia Flashcards
Onset is typically ____ in men compared to women
earlier (late teens/early 20s)
___show a bimodal distribution of onset of schizophrenia with a peak in the late 20s and another peak in middle age
women
Monozygotic twins have a ____ rate of concordant schizophrenia
50%
Newborns with fathers > _____ years old have an increased risk of schizo
60
There is evidence for too little dopamine in the ____ tract and too much in the _____ tract
mesocortical
mesolimbic
Heavy ____ use in adolescence is associated with increased risk
marijuana
Pathological findings include _____ ventricles and _____ cortical volume
enlarged
decreased
Decreased cortical volume appears to be due to: ______ (neuronal loss/reduced density of axons, dendrites, synaptic connections)
reduced density of axons, dendrites, synapses
Impaired _____ eye movements and _____ saccades are also seen
smooth pursuit
disinhibited
To be classified as schizophrenia, symptoms must be present for at least ____ months
6
Hallucinations are typically ____
auditory
The classic presentation of hallucinations in schizos:
multiple voices speaking to each other, commenting on patient’s thoughts and surroundings
____ are fixed false beliefs
delusions
Capgras syndrome:
delusion that a familiar person has been replaced by an imposter
Fregoli’s phenomenon:
delusion that persecutors or familiar people can assume the guise of strangers
In _____, speech wanders but eventually returns to the original point
circumstantiality
In ____, speech wanders and does not come back
tangentiality
Presentations of catatonia
mutism extreme psychomotor retardation repetitive purposeless movement waxy flexibility posturing/rigidity agitation