Schizophrenia Flashcards
Onset is typically ____ in men compared to women
earlier (late teens/early 20s)
___show a bimodal distribution of onset of schizophrenia with a peak in the late 20s and another peak in middle age
women
Monozygotic twins have a ____ rate of concordant schizophrenia
50%
Newborns with fathers > _____ years old have an increased risk of schizo
60
There is evidence for too little dopamine in the ____ tract and too much in the _____ tract
mesocortical
mesolimbic
Heavy ____ use in adolescence is associated with increased risk
marijuana
Pathological findings include _____ ventricles and _____ cortical volume
enlarged
decreased
Decreased cortical volume appears to be due to: ______ (neuronal loss/reduced density of axons, dendrites, synaptic connections)
reduced density of axons, dendrites, synapses
Impaired _____ eye movements and _____ saccades are also seen
smooth pursuit
disinhibited
To be classified as schizophrenia, symptoms must be present for at least ____ months
6
Hallucinations are typically ____
auditory
The classic presentation of hallucinations in schizos:
multiple voices speaking to each other, commenting on patient’s thoughts and surroundings
____ are fixed false beliefs
delusions
Capgras syndrome:
delusion that a familiar person has been replaced by an imposter
Fregoli’s phenomenon:
delusion that persecutors or familiar people can assume the guise of strangers
In _____, speech wanders but eventually returns to the original point
circumstantiality
In ____, speech wanders and does not come back
tangentiality
Presentations of catatonia
mutism extreme psychomotor retardation repetitive purposeless movement waxy flexibility posturing/rigidity agitation
A catotonic symptom associated with a medial emergency is _____
refusal to eat or drink
Abulia
indifference, lack of impulses to act or think
alogia
poverty of speech
avolition
lack of motivation
anhedonia
lack of enjoyment
acathexis
lack of appropriate emotional responses