Schizophrenia 3 Flashcards
Describe the two main positive symptoms in schziophrenia?
Hallucinations - false perceptions
Delusions - bizarre or irrational beliefs
What is the hypothesis for cause of positive symptoms at a physiological level 1?
Dysfunction of the system used by brain to alert about self-generated motor commands.
What is the hypothesis for cause of positive symptoms at a physiological level 2?
Loss of distinction between relevant and irrelevant stimuli - was it me producing the action.
What role does predictability play in positive symptoms?
Abnormal prediction error may be at the root of + positive symptoms.
Describe some negative symptoms, primary & secondary?
social anxiety, poverty of speech, flat affect, depression, impairment of voluntary movement.
Describe schizophrenic speech.
Intact grammar, incoherent content, bizarre pattern of speech
Describe 1 -3 cognitive symptoms
speed of processing
Attention vigilance
Working memory
Describe 4 - 6 cognitive symptoms
Verbal learning & memory
Visual learning & memory
Reasoning & problem solving (exec functions)
Describe 7th cognitive symptom
Social cognition.
What is happening with dopamergenic neurons in a normal state?
They’re sent back on a loop to the prefrontal cortex
What is happening with dopamergenic neurons in a schizophrenic?
they’re not sent back on a loop to the prefrontal cortex.
What are positive symptoms?
add something to the experience of the patient i.e. hallucinations
What are negative symptoms?
subtract from normal behaviour - i.e. ability to function, speak etc.
What are cognitive symptoms?
Inability to think clearly, apply logic, speaking structure.
