Schizophrenia 1 Flashcards
What are the type of symptoms schizophrenia is characterised by?
Positive symptoms -
Negative symptoms
Cognitive abnormalities
Describe + symptoms
not found in healthy people e.g. hallucinations, delusions.
Describe - symptoms
blunted responses, withdrawal from social interaction, lack of motivation.
Describe cognitive symptoms
poor working memory - lack of exec. function
When do symptoms manifest
late adolescence, early adulthood
Describe 2 of the 5 DSM symptoms for diagnosis in criterion A over a 1 month period
Delusion Hallucination Disorganised speech Gross disorganisation or catatonic behavioiur Neg symptoms
Whats criterion B & C
b - Social or occupational dysfunction
c - duration of 6 months
Whats criterion D & E
d - schizoaffective mood disorder
e - substance/general mood condition exclusion
Whats criterion F
relationship to global development delay or autism spectrum disorder
Genetic predisposition for MZ twins and DZ twins
MZ - 50% and DZ 15%
3 structural abnormalities
1 - Frontal lobe abnormality
2 - Medial temporal lobe
3 - enlarged lateral and 3rd ventricle
Microscopic anbormalities
grey matter - reduced dendrite complexity
white matter
functionality