Schizophrenia 1 Flashcards

1
Q

What are the type of symptoms schizophrenia is characterised by?

A

Positive symptoms -
Negative symptoms
Cognitive abnormalities

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2
Q

Describe + symptoms

A

not found in healthy people e.g. hallucinations, delusions.

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3
Q

Describe - symptoms

A

blunted responses, withdrawal from social interaction, lack of motivation.

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4
Q

Describe cognitive symptoms

A

poor working memory - lack of exec. function

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5
Q

When do symptoms manifest

A

late adolescence, early adulthood

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6
Q

Describe 2 of the 5 DSM symptoms for diagnosis in criterion A over a 1 month period

A
Delusion
Hallucination
Disorganised speech
Gross disorganisation or catatonic behavioiur
Neg symptoms
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7
Q

Whats criterion B & C

A

b - Social or occupational dysfunction

c - duration of 6 months

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8
Q

Whats criterion D & E

A

d - schizoaffective mood disorder

e - substance/general mood condition exclusion

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9
Q

Whats criterion F

A

relationship to global development delay or autism spectrum disorder

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10
Q

Genetic predisposition for MZ twins and DZ twins

A

MZ - 50% and DZ 15%

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11
Q

3 structural abnormalities

A

1 - Frontal lobe abnormality
2 - Medial temporal lobe
3 - enlarged lateral and 3rd ventricle

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12
Q

Microscopic anbormalities

A

grey matter - reduced dendrite complexity
white matter
functionality

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