Schizophrenia 2 Flashcards
what does CNV stand for and mean?
copy number variants (means a specific genetic factor)
how is there variation in the 16p11.2 gene causing schizophrenia?
either deletion or duplication. the 16th chromosome which has genes that are either deleted or duplicated or typical
a denovo mutation _____ chances of schizophrenia
increases
what are some of the physical brain changes in a schizophrenic patient?
enlarged ventricles smaller hippocampus smaller cortex temporal lobe degeneration brain volume shrinkage neurodegeneration loss of brain matter
why doesn’t a brain scan show that anatomy is the cause?
anatomical change may be due to environmental factors such as stress, drugs…not necessarily the cause
severe loss of ____ _____ matter can be shown in adolescents from 12+ years
gray matter
what is the difference in eye movements between a normal person and a person with schizophrenia?
schizophrenia have jerky non smooth pursuit compared to normal smooth pursuit following stimulus
what cognitive tasks do schizophrenics suffer from due to jerky eye movements?
disorientation
reading tasks
executive planning tasks (card sorting task into colour, shape, number)
give an example of a cognitive defect?
orientating response is attenuated
give an example of a schizophrenic cognitive bias?
over report confrontational interactions
give examples of attentional biases in schizophrenia
over attend to negative stimuli
delusions
similar to anxiety
give an example of reasoning biases in schizophrenia
jumping to conclusions
give an example of interpretational biases in schizophrenia
hearing voices
what is the idea behind double blind and paradoxical communication?
contradicting messages - verbal message may contradict the implied message therefore both become invalid
what are the family aspects of schizophrenia?
- double blind and paradoxical communication
- communication deviance
- expressed emotion