Schizophrenia 2 Flashcards

(28 cards)

1
Q

what does CNV stand for and mean?

A

copy number variants (means a specific genetic factor)

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2
Q

how is there variation in the 16p11.2 gene causing schizophrenia?

A

either deletion or duplication. the 16th chromosome which has genes that are either deleted or duplicated or typical

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3
Q

a denovo mutation _____ chances of schizophrenia

A

increases

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4
Q

what are some of the physical brain changes in a schizophrenic patient?

A
enlarged ventricles
smaller hippocampus
smaller cortex
temporal lobe degeneration
brain volume shrinkage
neurodegeneration
loss of brain matter
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5
Q

why doesn’t a brain scan show that anatomy is the cause?

A

anatomical change may be due to environmental factors such as stress, drugs…not necessarily the cause

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6
Q

severe loss of ____ _____ matter can be shown in adolescents from 12+ years

A

gray matter

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7
Q

what is the difference in eye movements between a normal person and a person with schizophrenia?

A

schizophrenia have jerky non smooth pursuit compared to normal smooth pursuit following stimulus

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8
Q

what cognitive tasks do schizophrenics suffer from due to jerky eye movements?

A

disorientation
reading tasks
executive planning tasks (card sorting task into colour, shape, number)

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9
Q

give an example of a cognitive defect?

A

orientating response is attenuated

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10
Q

give an example of a schizophrenic cognitive bias?

A

over report confrontational interactions

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11
Q

give examples of attentional biases in schizophrenia

A

over attend to negative stimuli
delusions
similar to anxiety

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12
Q

give an example of reasoning biases in schizophrenia

A

jumping to conclusions

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13
Q

give an example of interpretational biases in schizophrenia

A

hearing voices

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14
Q

what is the idea behind double blind and paradoxical communication?

A

contradicting messages - verbal message may contradict the implied message therefore both become invalid

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15
Q

what are the family aspects of schizophrenia?

A
  1. double blind and paradoxical communication
  2. communication deviance
  3. expressed emotion
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16
Q

critical, harsh emotions in families with schizophrenia, blaming patients for not controlling themselves, high score of this view symptoms as controllable = what family aspect?

A

expressed emotion

17
Q

low ____ is linked to schizophrenia

18
Q

what is the sociogenic hypothesis?

A

low SES may experience more stressors and stress happens before psychotic episodes

19
Q

what is the social drift hypothesis?

A

those with schizophrenia have difficultly with employment and social life and drift to lower SES

20
Q

does Davey state that parental SES at the time of birth is or isn’t associated with increased schizophrenic risk in the child?

A

not associated

21
Q

what was Rosenhan (1973) experiment on schizophrenia?

A

ppts pretended to be schizophrenic and sent to psych wards

22
Q

what are the major cognitive theories of schizophrenia?

A

Seligman’s attributional model

theory of mind

23
Q

Seligman’s attributional model is attributions of negative events. what are the 3 dimensions to this model?

A

internal vs. external
global vs. specific
stable vs unstable

24
Q

if negative events are interpreted as _______, _______, ________ this could lead to depression

A

internal
global
stable

25
what is the attribution style in psychosis that can lead to delusions?
EXTERNAL global stable
26
why will schizophrenic patients have difficulties with ToM tests?
ToM is distorted and exaggerated
27
what are the different ways to treat schizophrenia?
``` social skills training CBT reattribution therapy personal therapy cognitive remediation training family interventions ```
28
what are different family interventions for schizophrenia?
psychoeducation supportive family management applied family management community care