Schizophrenia Flashcards

1
Q

Define schizophrenia

A

Hallucinations and/ or delusions qualitatively different from normal experiences

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2
Q

What are some risk factors for schizophrenia?

A

Males, working class, inner city, cannabis, low IQ and genetic risk

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3
Q

What are Schneider’s 1st rank symptoms?

A

Auditory hallucinations, thought disorders, passivity phenomena and delusional perceptions

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4
Q

What are some positive symptoms of schizophrenia?

A

Auditory hallucinations, broadcasting of thoughts, control issues, delusional perceptions, cotard delusions and word salad

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5
Q

What is a cotard delusion?

A

Belief by a patient that they are dead

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6
Q

What is broadcasting of thoughts?

A

Belief that thoughts are being heard by others and thought echo

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7
Q
A
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8
Q

What is word salad?

A

Speech contains random words and phrases that is confused and lacks meaning

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9
Q

What is thought blocking?

A

Involuntary silence in the middle of speech and then changing to another topic

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10
Q

What are negative symptoms of schizophrenia?

A

Loss of usual abilities and experiences, socially appropriate behaviour and social withdrawal

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11
Q

What is avolition?

A

Loss of motivation to carry out goal-related activities

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12
Q

What is alogia?

A

Speech poverty - reduced fluency and quality with delayed responses

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13
Q

What is affective blunting?

A

Decreased ability to express facial expressions and emotion

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14
Q

What are secondary symptoms?

A

Symptoms that occur as a result of other symptoms such as unemployment, loss of social relationships and depression

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15
Q

Give an example of the most common typical first generation antipsychotic

A

Haloperidol

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16
Q

What are the common side effects of typical 1st gen antipsychotics?

A

Extrapyramidal side effects

17
Q

What is tardive dyskinesia?

A

Repetitive movements of the face such as lip smacking and excessive blinking

18
Q

Name the most common atypical second generation antipsychotic?

A

Risperidone

19
Q

Which atypical second generation antipsychotic has the fewest side effects?

A

Apiprazole

20
Q

What side effect is more common with 2nd generation antipsychotics?

A

Weight gain

21
Q

What is a serious side effect of Clozapine?

A

Agranulocytosis

22
Q

When is Clozapine indicated?

A

When patients have not responded to 2 other antipsychotics

23
Q

What threshold is reduced in Clozapine treatment?

A

Seizures are more likely

24
Q

What blood test is elevated in neuroleptic malignant syndrome?

A

Creatinine kinase

25
Q

What is FEVER for neuroleptic malignant syndrome?

A

Fever over 38
Encephalopathy
Vital signs - tachycardia and labile BP
Enzymes - raised CK
Rigidity