Depression

Question 1

How long do symptoms need to be present for diagnosis?

Answer 1

2 weeks

Question 2

What is anhedonia?

Answer 2

Decreased interest or pleasure in most activities most of the day

Question 3

What is 1st line for severe depression and give some long and short-term side effects?

Answer 3

ECT
Short term - muscle aches, nausea and headache
Long-term - persistent memory loss

Question 4

How long must antidepressants be taken for?

Answer 4

6 months

Question 5

What is the maximum dose of Sertraline?

Answer 5

200mg

Question 6

Name some SSRIs?

Answer 6

Sertraline
Fluoxetine
Citalopram
Paroxetine

Question 7

What is the 1st line SSRI for under 18s?

Answer 7

Fluoxetine

Question 8

What can Citalopram cause on ECG?

Answer 8

Prolonged QT

Question 9

What must be prescribed if an SSRI is taken alongside an NSAID?

Answer 9

PPI - Omeprazole

Question 10

What must be avoided co-prescribing with an SSRI?

Answer 10

Sumatriptan

Question 11

What is the follow-up for SSRI?

Answer 11

If under 25, they need to be followed up within 1 week because there is an increased suicide risk on initiation

Question 12

Give 2 examples of an SNRI?

Answer 12

Venlafaxine
Duloxetine

Question 13

Give an example of a TCA?

Answer 13

Amitriptyline

Question 14

Give 3 side effects of TCAs?

Answer 14

Anticholinergic - dry mouth, constipation, urinary retention
Antiadrenergic - postural hypotension, syncope
Antihistaminergic - sedation and weight gain