Schizophrenia Flashcards
C and C of Schizophrenia-
What is schizophrenia?
Inability to distinguish their own thoughts and ideas from reality
C and C of Schizophrenia-
What other condition if schizophrenia confused with?
Split personality disorder
C and C of Schizophrenia-
Is schizophrenia more common in men or women?
Men
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Is schizophrenia more common in cities or the countryside?
Cities
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Which class is schizophrenia more common in?
The working class
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What do we use to diagnose mental health conditions?
DSM-5
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What does using DSM-5 help?
Increases reliability
Decreases subjectivity
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What is a positive symptom?
A symptom taht you gain fro an illness or did not have before the illness
C and C of Schizophrenia-
What is as negative symptom?
The parting has lost something that they had before the illness
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What are delusions?
Believe it something that is not true
C and C of Schizophrenia-
What is speech poverty?
When speech becomes less fluent
C and C of Schizophrenia-
What is avolition?
A lack of motivation or drive
C and C of Schizophrenia-
What are hallucinations?
Sensing something that isn’t there
C and C of Schizophrenia-
What are delusions of grandeur?
When someone believe they are like god
C and C of Schizophrenia-
What are delusions of persecution?
When you believe Dan individual is out to get you
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What are delusions of control, influence and passivity?
Belief someone else is controlling your thoughts or actions
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What are auditory hallucinations?
You think you hear something
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What are visual hallucinations?
You believe that you see something
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What are somatosensory hallucinations?
You believe you can feel something
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What is speech poverty also known as?
Allgolia
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What is another word for avolition?
Apathy
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What do you need to have so you can be diagnosed with schizophrenia? (Minimum 2)
At least one of: delusions, hallucinations or disorganised speech
Disorganised behaviour or negative symptoms
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How long must the patient be disturbed for before they can be diagnosed?
Mist have symptoms for at least a month
And must be disturbed for at least 6 months
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What do symptoms need to cause?
A negative effect on some area of their life
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What must symptom snot be due to?
Other causes, such as drug use or another illness
C and C of Schizophrenia- reliability-
What are the two definitions of reliability?
Consistency over time
Consistency between doctors
C and C of Schizophrenia- reliability-
What is the first issue?
Differnt e between clinicians
C and C of Schizophrenia- reliability-
What is the second issue?
Difference between patients
C and C of Schizophrenia- reliability-
What are the causes of issue one?
The classification system may be interpreted differently by different observers
C and C of Schizophrenia- reliability-
What are the causes of issue two?
Culture- if the culture of patient vs psychiatrist is different it may cause misinterpretation of behaviour
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C and C of Schizophrenia- validity-
What are the two definitions of validity?
Whether you are measuring the thing you are trying to measure.
Whether the results are true.
C and C of Schizophrenia- validity-
What is symptom overlap?
When a disorder has no pathognomic symptoms (exclusive to the disorder)
C and C of Schizophrenia- validity-
What is the basic overview of symptom overlap?
Symptoms are not just present for schizophrenia but other disorders too
C and C of Schizophrenia- validity-
What is co-morbidity?
When an individual suffers with more than one disorder at a time
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What is an example of co-morbidity?
An individual develops depression as a result of the schizophrenia diagnosis
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Biological explanations of schizophrenia-
How much of the genes are shared between Mz twins?
100%
Biological explanations of schizophrenia-
How much genetic informant it on is shared between Dz reins?
50%
Biological explanations of schizophrenia-
How much genetic information is shared between half siblings?
25%
Biological explanations of schizophrenia-
How much genetic information is shared between cousins?
12.5%
Biological explanations of schizophrenia-
Who conducted the family studies?
Gottesman (1991)
Biological explanations of schizophrenia- FS-
What were the findings of Gottesman study?
Sharing more genetics with someone who has schizophrenia makes you more likely to have it
Biological explanations of schizophrenia-
Who did the studies on candidate genes?
Ripke (2014)
Biological explanations of schizophrenia- CG-
Is schizophrenia polygenic?
Multiple genes have been linked to schizophrenia
Biological explanations of schizophrenia- CG-
What is a genome?
Looking at all the genetic material in a human rather than one gene
Biological explanations of schizophrenia- CG-
What do candidate genes lead to?
Biological changes that cause symptoms
Biological explanations of schizophrenia- CG-
What was Ripkes study?
Combined all previous genetic information on the genome on schizophrenia
Biological explanations of schizophrenia- CG-
What did Ripke find?
108 separate genes are associated with the development of schizophrenia
Biological explanations of schizophrenia- CG-
What is aetiologically heterogeneous?
Different combinations of factors can lead to schizophrenia
Biological explanations of schizophrenia- RoM-
What is the role of mutation?
Genetic manipulation can still be found even if the family does not have schizophrenia in the family history
Biological explanations of schizophrenia- RoM-
What can cause genetic mutation?
Radiation, poison, or infection
Biological explanations of schizophrenia- RoM-
What evidence is there to back up the role of mutation?
Positive correlation between parental age (associated with increases sperm mutation) and risk of schizophrenia (0.7% under 25, over 2^ after 5p)
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Psychological explanations do schizophrenia- DBT-
Who conducted the double blind theory?
Bateson (1972)
Biological explanations of schizophrenia- N-
What is the original dopamine hypothesis?
High levels of dopamine in the sub royal areas of the brain cause schizophrenia (found as schizophrenia is similar to Parkinson disease )
Biological explanations of schizophrenia- N-
What is high levels of dopamine called?
Hyperdopaminergia
Biological explanations of schizophrenia- N-
What symptoms are high levels of dopamine associated with?
Positive symptoms (delusions and hallucinations)
Biological explanations of schizophrenia- N-
What is the revised dopamine hypothesis?
Low levels of dopamine can explain negative symptoms
Biological explanations of schizophrenia- N-
What is hypodopaminergia?
Low levels of dopamine in the subcortal areas of the brain