Schizophrenia Flashcards
Positive Symptoms
A01
Syptoms which add something new to the patients life
* hallucinations
* delusions
* speech disorganisation
Negative Symptoms
A01
Symptoms which take something away from the sufferer’s life
* speech poverty
* avolition
Schizophrenia
A01
A severe mental disorder that affects 1% of the population, where the sufferer cannot distinguish between the real and imagined
Diagnosis
A01
DSM-5
* 2 positive symptoms
* disturbance lasting 6+ months
* failure to function
ICD-10
* 2 negative or 1 positive symptom
* includes a range of subtypes such as paranoid schizophrenia
Classification and Diagnosis
A03
- Criterion validity (39 vs 69 out of 100)
- Culture bias
- Co-morbidity (50% depression)
- Gender bias
Typical Antipsychotics
A01
Dopamine agonists, based on the old dopamine hypothesis
* Blocks action of D2 receptors
* Reduces positive symptoms
* Can cause side effects
Atypical Antipsychotics
A01
Based on the new dopamine hypothesis
* designed to reduce side effects
* blocks D2 receptors temporarily to allow for normal dopamine transmission
* acts on serotonin and glutamate
* reduces positive and negative symptoms
Drug Treatments
A03
- Side effects
- Effectiveness
- Issues with research
- Atypical better than typical
Diathesis Stress
A01
A person who has a vulnerability to develop SZ, but only develops it after encountering a stressor
Diathesis
* Genes
* Complications with pregnancy
* Childhood trauma
Stress
* family dysfunction
* trauma
* general life stress
* cannabis use
Treat with CBT and drugs
Diathesis Stress
A03
- Concordance
- Parenting (Tiernari)
- Treatment
CBT for halucinations
A01
Explains symptoms as being due to malfuctioning systems in the brain
Does not fix symptoms, but helps with coping
CBT for Delusions
A01
ABCDE model
* disputes beliefs through discussions
Critical collaborative analysis
* gentle questioning to help patient challenge beliefs
CBT
A03
- NICE (reduces hospitalisation and symptoms)
- Quality of evidence is mixed
- Independent effect
- General evaluation
Family Therapy
A01
Family centred therapy used alongside other treatment
Psychoeducation to teach family about SZ
* Improve communication
* Reduce conflict
* Teach practical coping skills
* Teach signs of relapse
* Create a more supportive home environment
Family Therapy
A03
- Effectiveness (26% rerlapse vs 50% drugs)
- Appropriateness (cheeper)
- Effectiveness (medication compliance)
- Difficult to assess individually