Schizophrenia Flashcards
What are positives symptoms of SZ?
Things that are added to normal behaviour
Hallucinations, delusions
What are negative symptoms of SZ?
Things missing from expected behaviour
Speech poverty
What did Rosenhan conduct, find and what does this go against?
Being sane in insane places.
All but one pseudo-patient wrongly diagnosed with SZ
Suggests, in 1970’s, SZ had low validity
What did Cheniaux find and what does this go against?
ICD : 68% diagnosed with SZ
DSM : 39% diagnosed with SZ
Suggests low validity
What did Osorio find and what does this support?
Used OPCRIT (operationalised checklist). Inter-rater reliability was .97
SZ diagnosis more reliable
Candidate genes - what is SZ now thought to be?
Polygenic
What did Ripke find and what does this suggest?
108 separate candidate genes
No definite genetic cause for SZ
What did Tienari find and what does this support?
Finnish adoption study
Biological mothers has SZ
7% of adoptees developed SZ
Genetic cause of SZ
Why is genetic mutations relevant to inheriting SZ?
New mutation of genes can be the cause
Positive correlation between parental age and SZ
What did Gottesman find and what does this suggest?
Positive correlation between SZ and genes. 48% MZ and 17% DZ
Suggests there is a genetic cause but not 100%
What are the positives to the dopamine hypothesis?
Antipsychotics work at treating symptoms for SZ so dopamine hypothesis correct
What receptors cause SZ
Abnormally high D2 receptors
What are the environmental factors that cause SZ?
Birth complications
Childhood trauma
Smoking high canabis
What is the dopamine hypothesis? New and old
Old : SZ patients produced more dopamine than non
New : hyperdopaminergia (more dopamine in broccas area) + symptoms
Hypodomaminergia (less dopamine in prefrontal cortex) - symptoms
Who founded the family dysfunction explanation and what does this suggest?
Reichman - schizophrenogenic mother was cold, harsh and criticising
What does EE stand for and what does this mean?
Expressed emotion
Family express negative emotion loudly, aggressive behaviour