schizophrenia Flashcards

1
Q

what are 5 key features of schizophrenia

A

delusions, hallucinations, disorganized thinking, abnormal motor behaviour, negative symptoms

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2
Q

define neologisms

A

madeup word that have a meaning for the person but no meaning to others

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3
Q

define echolalia

A

repeating anothers words

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4
Q

define clang associations

A

choosing words based on sound (bang)

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5
Q

define word salad

A

jumble of words that is meaningless

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6
Q

define anergia

A

lack of energy

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7
Q

define anhedonia

A

inability to experience pleasure

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8
Q

define avolition

A

reduced motivation, inability to initiate tasks

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9
Q

define alogia

A

poverty of speech

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10
Q

what are 4 key first generation antipsychotics

A

chlorpromazine, haldol, trifiuperazine, zudopenthioxol

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11
Q

what are 2 major side effects of first generation antispychotics

A

eps, tardive dyskinesia

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12
Q

what causes eps

A

dopamine blockage

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13
Q

3 overarching signs of eps

A

acute dystonia, akathisia, psudoparkinsonism

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14
Q

acute dystonia presentation

A

sustained contraction of muscles

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15
Q

how do you treat acute dystonia

A

IM congention or IM benadryl

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16
Q

presentation of akathisia

A

inner restlessness, pacing, fidgeting

17
Q

presentation of pseudoparkinsonism

A

tremor, shuffling gait, muscle stiffening

18
Q

6 second generation (atypical) antipsychotics

A

clozaril, risperidone, lurasidone, olanzapine, quetiapine, ziprasidone

19
Q

what is a major adverse effect of clozaril

A

agranulocytosis

20
Q

3 third generation antipsychotics

A

aripriprazole, cariprazine, brexipiprazole

21
Q

what do third generation anypsychotics do

A

stabilize dopamine by decreasing it in some brain regions and increasing it in other regions

22
Q

how does neuroleptic malignant syndrome occur

A

acute reduction of dopamine

23
Q

what are 6 signs of neuroleptic malignant syndrome

A

decreased LOC, increased muscle rigidity, fever, sweating, drooling, change in breathing

24
Q

what med can be given to reduce muscle rigidity associated with neuroleptic malignant syndrome

A

bromocriptine