schizophrenia Flashcards
what are 5 key features of schizophrenia
delusions, hallucinations, disorganized thinking, abnormal motor behaviour, negative symptoms
define neologisms
madeup word that have a meaning for the person but no meaning to others
define echolalia
repeating anothers words
define clang associations
choosing words based on sound (bang)
define word salad
jumble of words that is meaningless
define anergia
lack of energy
define anhedonia
inability to experience pleasure
define avolition
reduced motivation, inability to initiate tasks
define alogia
poverty of speech
what are 4 key first generation antipsychotics
chlorpromazine, haldol, trifiuperazine, zudopenthioxol
what are 2 major side effects of first generation antispychotics
eps, tardive dyskinesia
what causes eps
dopamine blockage
3 overarching signs of eps
acute dystonia, akathisia, psudoparkinsonism
acute dystonia presentation
sustained contraction of muscles
how do you treat acute dystonia
IM congention or IM benadryl
presentation of akathisia
inner restlessness, pacing, fidgeting
presentation of pseudoparkinsonism
tremor, shuffling gait, muscle stiffening
6 second generation (atypical) antipsychotics
clozaril, risperidone, lurasidone, olanzapine, quetiapine, ziprasidone
what is a major adverse effect of clozaril
agranulocytosis
3 third generation antipsychotics
aripriprazole, cariprazine, brexipiprazole
what do third generation anypsychotics do
stabilize dopamine by decreasing it in some brain regions and increasing it in other regions
how does neuroleptic malignant syndrome occur
acute reduction of dopamine
what are 6 signs of neuroleptic malignant syndrome
decreased LOC, increased muscle rigidity, fever, sweating, drooling, change in breathing
what med can be given to reduce muscle rigidity associated with neuroleptic malignant syndrome
bromocriptine
