Schizophrenia Flashcards

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1
Q

What is Schizophrenia?

A

A severe mental disorder where contact with reality and insight are impaired
An example of psychosis.

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2
Q

Define Positive Symptoms of Schizophrenia

A

Atypical symptoms of Schizophrenia experienced in addition to normal experiences.
eg. hallucinations, delusions

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3
Q

Define Negative Symptoms of Schizophrenia

A

Atypical experiences that represent the loss of a usual experience such as a loss of clear thinking or motivation
eg. Avolition, speech poverty

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4
Q

Define Hallucinations

A

A positive symptom of schizophrenia.

Sensory experiences that have either no basis in reality or are distorted.

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5
Q

Define Delusions

A

A positive symptom of Schizophrenia.
They involve beliefs that have no basis in reality eg. believing they are someone else or they are the victim of a conspiracy.

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6
Q

Define Speech Poverty

A

Negative symptom of schizophrenia.

Involves reduced frequency and quality of speech.

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7
Q

Define Avolition

A

Negative symptom of Schizophrenia

Involves loss of motivation to carry out tasks and results in lowered activity levels.

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8
Q

Define Co-morbidity

A

Occurrence of 2 disorders or conditions together for example schizophrenia and a personality disorder
When 2 disorders are frequently diagnosed together it calls into questions the validity of classifying the 2 separately

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9
Q

Define Symptom Overlap

A

Occurs when 2 or more conditions share symptoms

Calls in to question the validity of classifying the two disorders separately

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10
Q

Evaluation points of Diagnosis and Classification

A
Good reliability (Osorio et al. 2019)
Low validity (Cheniaux 2009)
Co-morbidity 
Gender Bias 
Culture Bias 
Symptom overlap
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11
Q

Who did Family studies on Schizophrenia?

Conclusion?

A
Gottesman's 1991
2% chance if Aunt with SZ
9% chance if sibling with SZ
48% chance if identical twin with SZ
correlation represents genes and environments because
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12
Q

Who did the study on Candidate genes?

A

Ripke et al. 2014
3700 SZ patients compared with 113000 controls
108 genetic variations were associated with increased risk of SZ

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13
Q

SZ is polygenic and different studies have found different candidate genes so it is ____________ ___________

A

aetiologically heterogeneous

-different combinations of factors, including genetc variation can lead to the condition

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14
Q

Evaluation points for genetic basis of schizophrenia

A

Research support

-Tienari and

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