Schizophrenia Flashcards
What is Schizophrenia?
A severe mental disorder where contact with reality and insight are impaired
An example of psychosis.
Define Positive Symptoms of Schizophrenia
Atypical symptoms of Schizophrenia experienced in addition to normal experiences.
eg. hallucinations, delusions
Define Negative Symptoms of Schizophrenia
Atypical experiences that represent the loss of a usual experience such as a loss of clear thinking or motivation
eg. Avolition, speech poverty
Define Hallucinations
A positive symptom of schizophrenia.
Sensory experiences that have either no basis in reality or are distorted.
Define Delusions
A positive symptom of Schizophrenia.
They involve beliefs that have no basis in reality eg. believing they are someone else or they are the victim of a conspiracy.
Define Speech Poverty
Negative symptom of schizophrenia.
Involves reduced frequency and quality of speech.
Define Avolition
Negative symptom of Schizophrenia
Involves loss of motivation to carry out tasks and results in lowered activity levels.
Define Co-morbidity
Occurrence of 2 disorders or conditions together for example schizophrenia and a personality disorder
When 2 disorders are frequently diagnosed together it calls into questions the validity of classifying the 2 separately
Define Symptom Overlap
Occurs when 2 or more conditions share symptoms
Calls in to question the validity of classifying the two disorders separately
Evaluation points of Diagnosis and Classification
Good reliability (Osorio et al. 2019) Low validity (Cheniaux 2009) Co-morbidity Gender Bias Culture Bias Symptom overlap
Who did Family studies on Schizophrenia?
Conclusion?
Gottesman's 1991 2% chance if Aunt with SZ 9% chance if sibling with SZ 48% chance if identical twin with SZ correlation represents genes and environments because
Who did the study on Candidate genes?
Ripke et al. 2014
3700 SZ patients compared with 113000 controls
108 genetic variations were associated with increased risk of SZ
SZ is polygenic and different studies have found different candidate genes so it is ____________ ___________
aetiologically heterogeneous
-different combinations of factors, including genetc variation can lead to the condition
Evaluation points for genetic basis of schizophrenia
Research support
-Tienari and