Schistosomiasis Flashcards

1
Q

What is the infective stage for humans in schistosomiasis? (Harrison pp 1423)

A

Cercariae (Blood Flukes)

Metacercariae (Biliary Flukes)

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2
Q

What compromise the blood flukes? (Harrison pp 1423)

A

Schistosoma mansoni, japonicum, intercalatum, mekongi, haemotobium

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3
Q

True or false, all trematodes are hermaphroditic except schistosoma. (Harrison pp 1423)

A

True

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4
Q

What are the examples of Biliary Flukes? (Harrison pp 1423)

A

Clonorchis senesis, Opistorchis viverrrini, Opistorchis felienus, Fasciola hepatica, Fasciola gigantica

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5
Q

What compromise the Intestinal Flukes? (Harrison pp 1423)

A

Fasciolopsis buski and Heterophyes herterophyes

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6
Q

It is a lung fluke that may be seen in crayfish or crabs and globally known except in North America and Europe. (Harrison pp 1423)

A

Paragonimus westermani

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7
Q

It is a blood flukes that is seen in the China, Philippines and Indonesia. (Harrison pp 1423)

A

Schistomiasis japonicum

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8
Q

It is a blood flukes that is seen in Southeast Asia. (Harrison pp 1423)

A

Schistomiasis mekongi

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9
Q

It is a Intestinal flukes that is seen with ingestion of a freshwater or brackish-water. (Harrison pp 1423)

A

Heterophyes heterophyes

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10
Q

It is a useful indicator of infection and has significance in protective and immunopathologic. (Harrison pp 1423)

A

Peripheral blood eosinophilia

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11
Q

It is the main adaptive mechanism of survival of schistosomiasis in human. (Harrison pp 1424)

A

Trilaminar to Heptalaminar

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12
Q

Sexually mature worms like S. mansoni, S. japonicum, S. mekongi and S. intercalatum goes to which part of the body and also where they deposit their ova? (Harrison pp 1424)

A

Intestinal veins

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13
Q

Sexually mature S. Haematobium goest to which part of the body and also where they deposit their ova? (Harrison pp 1424)

A

Pelvic Veins

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14
Q

True or False: All forms of Schistosoma infection are associated with subclinical systemic morbidities that cause significantly affect the physical and cognitive performance like growth stunting, undernutrition and aniemia. (Harrison pp 1425)

A

True

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15
Q

What are initially recruited in granuloma (Schistosomula) formation? (Harrison pp 1425)

A

Phagocytes
Antigen specific T cells
Eosinophils

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16
Q

What is recruited later in granuloma formation? (Harrison pp 1425)

A

Fibroblasts
Giant cells
B lymphocytes

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17
Q

Where does granuloma formation occurs? (Harrison pp 1426)

A

Perisinusoidal sites

18
Q

What happened if there is perisinusoidal portal blockage? (Harrison pp 1426)

A

Portal hypertension
Portosystematic collaterals at the esophageal junction
Esophageal varices

19
Q

It is characteristically as fibrosis at periportal but may be diffuse. (Harrison pp 1426)

A

Symmer’s clay pipe-stem fibrosis

20
Q

In Schistosomiasis haemotobium, the granuloma formation occurs in the lower end of the ureters that obstructs the urinary flow, which eventually leads to the following: (Harrison pp 1426)

A

Hydroureter

Hydronephrosis

21
Q

Secondary infertility or subfecundity may result that involves what areas of the of female’s genitals? (Harrison pp 1426)

A

FUO
Fallopian tubes
Uterus
Ovaries

22
Q

It is during the phase of cercarial invasion, a form of dermitis that usually involved the S. mansoni and S. japonicum. (Harrison pp 1426)

A

Swimmer’s Itch

23
Q

It is a serum like sickness like illness with fever, generalized lymphadenopathy and hepatosplenomegaly. (Harrison pp 1426)

A

Katayama Syndrome

24
Q

What is the main clinical manifestations of chronic shistosomiasis? (Harrison pp 1426)

A

Species dependent

25
It is the 1st clinical manifestation of hepatosplenic phase. (Harrison pp 1427)
Bleeding from esophageal varices
26
It is considered as human carcinogen. (Harrison pp 1427-1428)
Schistosoma haemotobium Clonorchis sinensis O. viverrini
27
Pulmonary schistosomiasis produces what disease? (Harrison pp 1427)
Acute necrotizing arteriolitis | Granuloma formation
28
What are the most common symptoms of pulmonary schistomiasis? (Harrison pp 1427)
Cough, fever and dyspnea
29
It is the 2nd most common cause of epilepsy in endemic area and caused by S. japonicum. (Harrison pp 1427)
Jacksonian epilepsy
30
It is associated with transverse myelitis. (Harrison pp 1427)
S. mansoni | S. haematobium
31
It is the considered as screening test for Schistosomiasis. (Harrison pp 1427)
FAST-ELISA
32
It is considered as confirmatory test for Schistosomiasis (Harrison pp 1427)
EITB (Enzyme-linked immunosorbent assay)
33
If suspected to have Schistosomiasis, what is would request for diagnostic? (Harrison pp 1427)
Kato Thick Smear
34
What is the treatment of choice for Schistosomiasis? (Harrison pp 1428)
Praziquantrel
35
What is the adult dose and duration to be given for S. japonicum and mekongi? (Harrison pp 1428)
Praziquantrel 20mg/kg, 3 doses in 1 day
36
What is the treatment of choice for Fasciola hepatica and Fasciola gigantica? (Harrison pp 1428)
Triclabendazole 10mg/kg ONCE
37
It is Chinese or oriental fluke and endemic among fish-eating mammals. (Harrison pp 1428)
Clonorchis sinensis
38
It is found on zoonitic cats and dogs. (Harrison pp 1428)
Opistochorchis viverrini | Opistochorchis felineus
39
Where do liver (Biliary) flukes matures? (Harrison pp 1428)
Bile cannaculi
40
It is related with cholangiocarcinoma. (Harrison pp 1428)
C. sinensis (China) | O. viverrini (Thailand)
41
It is endemic among sheep raising countries (Harrison pp 1428)
Fasciola hepatica | Fasciola gigantica
42
It is observed among patient with brownish sputum or frank hemoptysis. (Harrison pp 1429)
Pulmonary paragonimiasis