Schistosomiasis

Question 1

Which type of schistosomiasis tends to cause bloody urine?

Answer 1

Haematobium

Question 2

What are the animal reservoirs of schistosomiasis?

Answer 2

Baboons
Rats
Dogs (for S. Mekongi)

Question 3

What is the route of schistosomiasis worms through humans?

Answer 3

Skin –> lungs –> liver

Question 4

What symptoms does S. haematobium cause?

Answer 4

Haematuria
Dysuria/secondary UTI
Bladder fibrosis
Calcification
Obstructive uropathy
Bladder SCC

Question 5

Which types of schistosomiasis tend to affect the bowel?

Answer 5

S. Mansoni
S. Japonicum

Question 6

How can schistosomiasis be diagnosed?

Answer 6

1. Serology - CCA or CAA (circulating cathodic/anodic antigen)
2. Urine/stool microscopy x3

Question 7

How is schistosomiasis treated?

Answer 7

Single-dose 40mg/kg praziquantel

Question 8

How is schistosomiasis treated if S. Japonicum suspected/diagnosed?

Answer 8

Single-dose 60mg/kg praziquantel

Question 9

What is one of the commonest cause of death secondary to schistosomiasis?

Answer 9

Variceal bleeding (and therefore there is a role for endoscopy)

Question 10

How effective is treatment for schistosomiasis?

Answer 10

50-80% effective