SANS VII Flashcards
general
A 28 year-old healthy woman who delivered her second child 10 days ago presents with new onset headache. lethargy. and confusion. She has no focal deficits. A non-contrast head CT Is obtained and shown below. What is the most appropriate definitive treatment for this patient?
A Endovascular embolization
B Recombinant activated Factor VII
C Intravenous heparin infusion
D craniotomy for hematoma evacuation
E. Observation only
(C)
a 47 year old woman presented with a frost seizure and underwent magnetic resonance imaging of the brain with multi voxel spectroscopy. The spectroscopy shown in figure 1 is MOST consistent with what diagnosis :
A. bacterial abcess
B. Glial Neoplasm
C. Toxoplasmosis
D. Demyelinating Plaque
E. Meningioma
(B)
A 48 year-old man with a right middle cerebral artery distribution infarction. Despite aggressive medical and endovascular therapy, the artery remains occluded. Two days later he has a decline in mental status. His head CT is shown. What is the most likely explanation for the patient’s new neurological deterioration?
A. Occlusive Hyperemia B. Reperfusion syndrome
C. Hemorrhagic conversion
D. Cerebral Edema
E. Normal perfusion pressure breakthrough
(?)
The appropriate maintenance rate for IV fluid in a 2 week old child is: A. 4 ml/kg/hr B. 10 ml/kg/hr C. 2 ml/kg/hr D. 20 ml/kg/hr E. 1 ml/kg/hr
(?)
What factor MOST indicates the need for enhanced screening for coronary ischemia prior to general anesthesia for a neurosurgical procedure: A. male sex B. orthostatic intolerance C. age > 60 years D. surgical urgency E. neoplastic disease
(?)
A patient presenting for resection of a small parietal meningioma has a preoperative INR of 1.5. What is the likellh<5% D. 75%E. 95%
(?)
During the creation of a burr hole for a deep brain stimulator, an awake, sedated patient develops the sudden onset of coughing, hypotension, and hypoxia. The clinical presentation suggest which of the following complications: A. Intracranial hemorrhage B. Aspiration pneumonia C. Air embolism D. Tension pneumocephalus
(C)
In a Nationwide lnpatient Sample, the most common cause of perioperative visual loss (POVL) In 465,345 patients undergolng spinal fusion was: A Anterior ischemic optic neuropathy B Corneal abrasion C Cortical blindness D Posterior ischemic optic neuropathy E. Retinal vascular occlusion
(C)
In a 2009 study of 5.6 million patients who underwent the principal procedures of knee arthroplasty, cholecystostomy, hip/femur surgical treatment, spinal fusion, appendectomy, colorectal resection, laminectomy without fusion, coronary artery bypass grafting, and cardiac valve procedures from 1996 to 2005, cardiac and spinal fusion surgery had the highest rates of POVL. The national estimate in cardiac surgery was 8.64/10000. The American society of Anesthesiologists (ASA) class is designed to estimate what parameter: A. Patient physical status B. Age maximum of surgery C. Tolerable blood loss D. Surgical risk E. Operative mortality
(?)
The use of Intensive Insulin therapy to reduce blood glucose In critically Ill patients with aneurismal subarachnoid hemorrhage has teen associated with an increase In the Incidence of what complication? A. Myocardial ischemia and Infarction B. Hypoglycemic episodes C. All-cause in-hospit31 mortality D. seizures E. Surgical site infection
(?)
What is the BEST estimate of blood volume in a thirteen month old child weighing 10 kilograms? A. 700 ml B. 1000 ml C. 800 ml D 9OOml E. 600 ml
(?)
What is the maximal reduction in the cerebral metabolic requirement for oxygen (CMR02) achievable exclusively through the use of high-dose barbiturates? A. 50% B. 25% C.15% D. 75% E. 90%
(?)
What is the most concerning side effect or dexmedetomidine Infusion In ICU patients? A. Inhibition or the locus ceruleus B. Bradycardia c Systolic hypertension D. Respiratory depression E. Intracranial hypertension
(?)
Which anesthetic agent is least likely to precipitate EEG evidence or seizure activity? A Lidocaine B. Isoflurane C. Enflurane D. Propofol E. Sevoflurane
(?)
A 23 year old woman with complex partial seizures was Initially treated with phenytoin, then switched to carbamazepine, and is currently on levetiracetam after failing the first two therapies. After a seizure-free period of six months upon starting levetiracetam, she now has recurrence of 2-3 seizures/month. What is the most appropriate next step in her management? A. Evaluation for vagus nerve stimulation. B. Add-on therapy with oxcarbazepine. C. Switch to therapy with oxcarbazepine. D Evaluation for resective epilepsy surgery
(D)
A 32 yr old male with intractable seizures and a normal MRI scan undergoes a non Invasive evaluation. Based on scalp EEG and seu:ure semiology, he had subdural electrodes placed and seizures were localized to the left language dommant supplementary motor area Following surgical resectioo the patient will MOST likely exhibit : A. Temporary paresis on the left. B. Left inferior quadrantopsia C. Temporary Mutism D. Anosmia and Finger agnosia
(C)
Patients with subcortical band heterotopia are characterized by: A. Male predominance. B. Subependymal giant cell astrocytomas. C. Infantile spasms. D. X-linked migrational disorder
(D)
The MOST common clinical feature of medial temporal lobe seizures is: A. Visual aura. B. Ictal Oral Automatism C. Ictal bicycling movements D. Ipsilateral dystonic posturing
(B)
West’s syndrome is BEST characterized by which of the following seizure type : A. Primary and secondarily generalized B. Generalized tonic clonic C. Complex partial D. Infantile Spasm E. Atonic
(D)
West’s syndrome is best characterized by which of the following seizure type : A. Primary and secondarily generalized B. Generalized tonic clonic C. Complex partial D. Infantile Spasm E. Atonic
(D)
Which of the following structures is BEST described as lateral to the hippocampal complex (hippocampus, subiculum and parahippocampal gyrus)? A. Brain stem. B. Ambient cistern. C. Posterior cerebral artery. D. Fusiform gyrus E. Occulomotor nerve
(D)
A 27 year old male construction worker had the on set of new head aches. which began suddenIy while doing heavy lifting at work. He was seen at a local emergency room shortly after his symptoms began. Neurological examination. head CT and spinal fluid were said to be normal. Now he returns to the ER with persistent headaches and a left abducens palsy. The remainder of the neurological examination is normal. An MRI with gadolinium is shown. Spinal fluid has 95 lymphocytes. CSF protein is slightly elevated but the glucose is normal. The MOST likely diagnosis is:
A. Carcinomatous meningitis
B. spontaneous intracranial hypotension
C. Hypertrophic interstitial pachymeningitis
D. sarcoidosis
E. Lymphoma
(?)
A 29-year-old man comes to the emergency department after awakening that morning with deep, boring pain in the right ear and sagging of the right side of his face. Examination shows normal sensation in the affected area and there are no lesions on the pinna. Hearing is normal but he complains of increased sensitivity to sound in the right ear. A MR scan shows enhancement of the right facial nerve in the petrous bone. A photograph of him attempting to smile is shown. The MOST appropriate initial therapy should be: A. Oral prednison B. Oral Levaquin C. Observation only D. Oral acyclovir E. Surgical decompression of the right facial nerve
(?)
A 34 year old male who is 8 years post liver transplantation is seen in the emergency department complaining of blurred vision. He has visual hallucinations. He has no paresis but there is bilateral asterixes. His pupils and optic discs are normal. He is hypertensive. He has a grand mal seizure. His MRI scan is shown. Which of the following is the mOST likely diagnosis: A. Lymphoma B. Diffuse glioma C. Reversible posterior leukoencephalopathy D. Progressive multifocalleukoencephalopathy E. Ammonia intoxication with secondary cerebral edema
(?)
A 6-year-old boy is struck in the right temple by a baseball but does not lose consciousness. His older brother walks him home. He complains of headache and takes acetaminophen for the pain. He soon becomes delirious: screaming, fighting, and biting his parents who try to restrain him. When seen shortly thereafter in the local emergency department, he has normal pupils and no paresis. His mother has a history of migraine headaches. The MOST likely diagnosis is: A. Subclinical Seizure. B. Bitemporal Contusion. C. EPIDURAL HEMATOMA D. Metabolic Encephalopathy. E. MIGRAINE
?
A 65 year old presents with gradual onset: asymmetric weakness with proximal and distal atrophy. He has had multiple falls. Biopsy of the vastus latera lis is shown. What is the most likely diagnosis? A. amyotrophic lateral sclerosis B. Inclusion body myositis C. Polymyositis D. Dermatomyositis E. Toxic myopathy
?
A 7 year-old child of migrant farm workers presents with to the emergency room with a seizure. Parents describe 60 seconds of unresponsiveness with twitching movements of the right leg. Last month they noted several similar episodes when the child was sick with an ear infection. On examination in the EDI he is sleepy but arousal, with a moderate right hemiparesis! most prominent in the leg. An MRI of the brain is shown in the figure. Which of the following is the MOST appropriate diagnostic step? A. TB skin test B. needle biopsi C. 0pen resection D. Serum/CSF immunologic testing
?
A 74 year old man presents with progressive cognitive decline over one year. Occasional visual hallucinations. poor attention. short-term memory loss! and bilateral upper extremity rigidity. What is the most likely diagnosis? A. Alzheimer disease B. Dementia with Lew Bodies C. Multi-infarct dementia D. Wilson’s disease E. Pick’s disease
?
According to the World Federation of Neurology, amytrophic lateral sclerosis is diagnosed by which pattern of neurological dysfunction? A. Upper or lower motor neuron dysfunction without progression B. Isolated lower motor neuron dysfunction with progression C. Isolated upper motor neuron dysfunction with progression D. Both upper and lower motor neuron dysfunction with progression E. Both upper and lower motor neuron dysfunction without regression
?
This 7 year old boy has had difficulty with ambulation and gross motor skills since early childhood. He did not walk until age 17 months. His symptoms are getting progressively worse. Mental status is unimpaired, and cognitive development is normal. Based on this video clip. his MOST likely diagnosis is: A. Muscular Dystrophy B. Myelodysplasia C. Tethered cord syndrome D. McArdle’s disease E. Spinal cord tumor
?
What is the pathophysiological etiology of isolated unilateral weakness of dorsiflexion and ankle inversion? A. Peroneal mononeuropathy B. L5 Radiculopathy C. S 1 radiculopathy D. L4 radiculopathy E. Tibial mononeuropathy
?
What is the pathophysiological etiology of isolated unilateral weakness of dorsiflexion and ankle inversion? A. Peroneal mononeuropathy B. L5 Radiculopathy C. S 1 radiculopathy D. L4 radiculopathy E. Tibial mononeuropathy
?
Which of the following anti-epileptic agents would be BEST to use in a patient receiving multiple other medications extensively metabolized by the liver? A. Phenobarbital (Luminal) B. Levetiracetam (keppra) C. Carbamazepin (Tegretol) D. Phenytoin (Dilantin) E. Oxcarbazepine (Trileptal)
?
.5 year old child presents with macrocephaly and poor height and weight gain. He has just begun to walk, but has age appropriate language development. A head CT scan and MRI show a large pineal region lesion. Serum beta HCG and AFP are negative. The MOST appropriate procedures is: A. Endoscopic biobsy and CSF shunt placement B. Cerebral angiogram C. Stereotactic Biopsy D. Open biopsy and possible resection
D
A 10 year old boy with a history of aqueductal stenosis and CFS shunt present with nausea, vomitting and headache and a temperature of 100.5 he had a shunt revision for similiar symptoms 3 month ago. His brother has been sick lately too, with diarrhea and abdominal pain. His CT scan shows a ventricular catheter in good position and normal ventricular size. A shunt series is norma. The MOST appropriate diagnotic test is : A. None B. Shunt exploration C. Shunt tap D. ICP monitoring
C
What is the pathophysiological etiology of isolated unilateral weakness of dorsiflexion and ankle inversion? A. Peroneal mononeuropathy B. L5 Radiculopathy C. S 1 radiculopathy D. L4 radiculopathy E. Tibial mononeuropathy
?
What is the pathophysiological etiology of isolated unilateral weakness of dorsiflexion and ankle inversion? A. Peroneal mononeuropathy B. L5 Radiculopathy C. S 1 radiculopathy D. L4 radiculopathy E. Tibial mononeuropathy
?
Which of the following anti-epileptic agents would be BEST to use in a patient receiving multiple other medications extensively metabolized by the liver? A. Phenobarbital (Luminal) B. Levetiracetam (keppra) C. Carbamazepin (Tegretol) D. Phenytoin (Dilantin) E. Oxcarbazepine (Trileptal)
?
.5 year old child presents with macrocephaly and poor height and weight gain. He has just begun to walk, but has age appropriate language development. A head CT scan and MRI show a large pineal region lesion. Serum beta HCG and AFP are negative. The MOST appropriate procedures is: A. Endoscopic biobsy and CSF shunt placement B. Cerebral angiogram C. Stereotactic Biopsy D. Open biopsy and possible resection
D
A 10 year old boy with a history of aqueductal stenosis and CFS shunt present with nausea, vomitting and headache and a temperature of 100.5 he had a shunt revision for similiar symptoms 3 month ago. His brother has been sick lately too, with diarrhea and abdominal pain. His CT scan shows a ventricular catheter in good position and normal ventricular size. A shunt series is norma. The MOST appropriate diagnotic test is : A. None B. Shunt exploration C. Shunt tap D. ICP monitoring
C
A 10 year-old girl presents with signs of accelerated pubertal stage, convergence-retraction nystagmus, and impaired upward gaze. Which of the following lesions would likely be the cause of the findings described? A. Pontine glioma B. Pineal region tumor C. Acqueductal stenosis D. Multiple sclerosis
B
A 10-year-old boy presents compalining of headache and imbalance. Examination discloses mild pailedema, right-sided dysmetria, and taxia. Magnetic resonance imaging with gadolinium enhancememnt is shownin figure 1. The MOST important prognostic factor this patient is : A. The extent of resection of the enhancing mass B. The extent of resecion of the cyst walls C. The presence of endothelial proliferation of histology D. The presence of mitoses on histology E. The presence of hydrocephalus at presentation
A
A 15 year old male presents with severe low back pain. The pain responds poorly to ….. but responds well to aspirin. CT demonstrates a 1.5 cm dense lytic lesion of with a calcified nidus and circumferential sclerosis. What is the diagnosis? A. Osteochondroma B. Osteoid osteoma C. Hemangioma D. Oteoblastoma
B
A 15 year old patient with a history of prematurity and post-hemorrhagic hydrocephalus presents to the emergeny department with an intermittent fever of no higher than 100.2 deg . F, anorexia, and mild headache. His peripheral WBC is normal, at 9.3. The patient and his mother both deny the possibility of VP shunt malfunction. He states that “this is totally different than the symptoms i had 8 months ago when my shunt was blocked”. The MOST likely diagnos is : A. Gastroenteritis B. Pseudotumor cerebri C. Proximal shunt obstruction D. Bowel perforation E. Abdominal pseudocyst
E
A- 2-year-old child undergoes computed tomography for the preliminary complaint of macrocephaly (figure 1). He is developmentally normal and has normal results of the neurological examination without papilledema. Six months later, routine follow-up magnetic resonance imaging shows enlargement of the left middle fossa abnormality (figure 2) and repeat tasting reveals mild developmental delay and early papilledema. Which diagnosis is MOST likely: A. Arachnoid cyst B. Epidermoid C. Abscess D. astrocytoma
A
A year old presents with headache and vomitting. CT and MR imaging reveals the presence of a 4th ventricular tumor. A suboccipital craniotomy is performed for total resection of a medulloblastoma. Resection is followed protocol based chemotherapy and total neuroaxis radiotherapy. With a boost to the posterior fossa. Which endocrinological complication is the MOST likely after radiotherapy for a posterior fossa tumor in childhood? A. Diabetes insipidus B. Cushing’s syndrome C. Growth hormone deficiency D. Addison’s syndrome
C
A 6 year old child with a traumatic brain injury is intubated and appears agitated. His CT scan obtained within the last hour shows a left parietal contusion. Intracranial pressure monitoring via ventriculostomy shows sustained pressure above 20 mmHg, despite bucking againts the ventilator with minimal stimulation. His vital signs are within age appropriate limits and he apprears well hydrated. What is the most appropriate pharmacological management of this patient? A. Morphine and versed B. Pentobarbital C. Vecuronium D. Propofol
A
A 9-year-old male presented to his pediatrian with headaches and growth delay. Pathological specimens of his tumor obtained at operation are shown in the photomicrographs. What is the MOST likely diagnosis: A. Colloid cyst B. Craniopharyngioma C. Pilocytic astrocytoma D. Hypothalamic hamartoma E. Pituitary adenoma
B
A term infant is born with a cranial malformation in the occipital region (fig 1). Which diagnosis is MOST likely? A. Dermal sinus tract B. Chiari III malormation C. Myelomeningocele D. Anencephaly E. Encephalocele
E
An 8 year old girl present with years of chronic headaches that have worsened during the past 6 months and prgressive difficulty in school. She had previously been an ‘A student’ but her grades have dropped to Cs, and she complains of problems with memory, attention, and coordination. She has mild papilledema. You recommend endoscopic treatment of her obstructive triventricular hydrocephalus rather than VP shunt placement. During endoscopic exploration of the ventricular system, the MOST appropriate site for surgical fenestration is: A. Septum pellucidum superior to the fornices B. 3rd ventricle floor anterior to the infundibular recess C. 3rd ventricle floor anteior to the mammillary bodies D. Lamina terminalis above the suprachiasmatic recess
C
Children of mothers with diabetes mellitus have an increased insidence of which spinal disorder? A. Meningocele manque B. Sacral agenesis C. Spinal dysraphism D. Thoracic hemivertebrae E. Intraspinal lipomas
B
Current pediatric head injury guidelines suggest maintenance of the minimum cerebral perfusion pressure above 40 to 65 mmHg, depending on : A. Skull thickness B. Patient age C. Status of fontanelle D. Core temperature E. Time since injury
B
The incidence of myelomeningocele has decreased during the past decade. Before the 1980s, the incidence was 1 to 2 per 1000 live births. The current incidence is 3 per 10.000 live births. One reason for this decline may be the recommendation by physicians and obstetricians for women to supplement their folic acid intake. The american college of obstetrics and gynecology recommends the following supplementation guideline to all women from menarche to menopause: A. 400 micrograms every day B. 800 microgramsduring first trimester C. 4 gram every day D. 4 gram every week E. 400 micrograms after positive pregnancy test
A
- A PGY -2 resident has worked 75 hours In the current week. The resident began his call shift yesterday at 06:00. The resident had 2 days completely off work in the previous two weeks. During the call day, the resident admits a pediatric patient with a rare brain tumor. The next day, the resident hands off call responsibilities to another resident. However, he then stays to assist with a rare pediatric brain tumor resection until noon. Which ACGME duty hour rule applies? A. Adequate rest between duty periods B. Minimum days off C. Maximum duty period length D. In house call limitation E. 80 hour work week
C
A Type 2 error (false negative) in interpreting clinical trials occurs when: A. Inadequate informed consent was obtained in over half the cases. B. A treatment is found to be ineffective but the sample size is too small. C. A positive result relies on an incorrect statistical test D. The test is not randomized or controlled. E. Gender makeup of the experimental and control populations are not equal.
B
A medical device company is sponsoring a presentation regarding a new implant they have developed for treatment of spinal instability. The presentation is followed by a modest meal at a local restaurant. At the conclusion of the meal, the company representative passes out gifts to the attending physicians, as a “thank you” for taking time out of their personal lives to attend a work meeting. Which of the following gifts would be acceptable under the AMA code of ethics and Advamed guidelines? A. Tickets to professional basketball game the following week B. Textbook of spinal anatomy with company logo Imprinted on cover C. $100 gift certificate to restaurant D. Golf shirt with company logo displayed on sleeve
B