SAM II Exam I Material - Gastrointestinal Flashcards

1
Q

This is a specific antidote used in Tylenol toxicity

A

N-acetyl cysteine

N-acetyl cysteine treats acetaminophen (Tylenol) poisoning by binding the poisonous forms of acetaminophen that are formed in the liver

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Considering the risks and diagnostic value of each biopsy technique, which biopsy method is the best option for dogs with non-infiltrative/neoplastic liver disease?

  • FNA
  • Menghini tru-cut
  • Laparotomy/laparoscopy
A

Laparotomy/laparoscopy​

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

T/F: If you note microcytic, hypochromic anemia in a yorkshire terrier, this can be an indicator of poor iron metabolism associated with portosystemic shunts

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the drug of choice for treatment of histiocytic ulcerative colitis?

A

enrofloxacin

Since histiocytic ulcerative colitis is a bacterial infection, it is antibiotic responsive. Enrofloxacin is typically effective. It is critical to treat for at least 8 weeks (even if the patient feels normal by week 2). Stopping antibiotics before 8 weeks has been associated with recurrence of infection and resistance to enrofloxacin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Lady, a 6-year-old Labrador has been under your care for CH for 2 months. Today she presents like this. What do you recommend as the first line of treatment?

  • Drain all the fluid by abdominocentesis
  • Spironolactone at 2 mg/kg/day
  • Furosemide at 2 mg/kg/day
  • Colloid like hetastarch
A

Spironolactone at 2 mg/kg/day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

T/F: ALT and AST are very liver-specific

A

False

  • ALT is very liver specific*
  • AST is also from skeletal muscle and cardiac muscle*
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

T/F: Both cats and dogs with acute pancreatitis will regularly demonstrate abdominal pain

A

False

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

T/F: The current combination of tests with the best test accuracy for the diagnosis of acute pancreatitis is cPL and abdominal ultrasound

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is the specific treatment for aflatoxicosis?

A

Plasma & Vitamin K

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

T/F: Xylitol toxicosis is associated with hyperglycemia

A

False

Xylitol stimulates insulin release and results in hypoglycemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the role of H2 blockers and proton pump inhibitors in the medical treatment of esophagitis?

A

neutralize acid secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

T/F: Concurrent IBD, cholangiohepatitis and pancreatitis are common in cats

A

True

These concurrent diseases are referred to collectively as triaditis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What liver disease is associated with the highest mortality rate in cats?

A

hepatic lipidosis

Lipid accumulation in hepatocytes​ eventually results in loss of hepatic function.

  • Increased triglyceride deposition associated with starvation due to mobilization of fatty acids from lipid stores
  • Insufficient insulin – fat stores used for energy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Is the following clinical sign more associated with small bowel diarrhea or large bowel diarrhea:

weight loss and protein loss

A

small bowel (often in chronic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the mechanism of action of lactulose in resolving hepatic encephalopathy?

  • Laxative
  • Purgative
  • Resolves dysbiosis
  • Ion trapping
  • Resolves alkalosis
A

Ion trapping​

lactulose acidifies the GIT and traps ammonia; decreases absorption of harmful substances by increasing GIT transit​

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Current evidence based medicine supports the diagnosis of specific therapy for acute pancreatitis. Which therapy in dogs is not specifically indicated?

  • Crystalloid resuscitation
  • Fentanyl CRI
  • Broad spectrum antibiotics
  • Maropitant, NK1 receptor antagonist
A

Broad-spectrum antibiotics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Which of these is/are classic feature(s) of small bowel enteritis in contrast to large bowel enteritis?

  • mucous
  • tenesmus
  • dyschezia
  • hematochezia
  • low volume
  • hypocobalaminemia
A

hypocobalaminemia

hypocobalaminemia is more characteristic for small intestinal enteritis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

T/F: Both cats and dogs will have obvious ultrasonography changes in acute pancreatitis in >70% of cases

A

False

Cats are more prone to chronic pancreatitis than acute pancreatitis and it’s difficult to diagnose chronic pancreatitis on ultrasound

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

T/F: Steroids are indicated for treatment of hepatic lipidosis in cats

A

False!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

T/F: Both cats and dogs will frequently have cholangitis and enteritis accompanying pancreatitis

A

False

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

T/F: When using maropitant as an anti-emetic in acute liver disease, it is standard to decrease the recommended dose by ~25%

A

True

Maropitant is metabolized in the liver, so we generally decrease the dose by ~25% in our acute liver disease patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Which of these is not a good treatment for IBD in these cats?

  • Budesonide
  • Prednisolone
  • Metronidazole
  • Chlorambucil
  • Azathioprine
A

Azathioprine​

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

The most common form of pancreatitis in cats is:

A

chronic pancreatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

When submitting a liver biopsy, what special stain would you request if you want to confirm cirrhosis and fibrosis?

A

Masson’s trichome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

T/F: Hepatic encephalopathy (HE) can occur in acute or chronic liver disease as well as portosystemic shunts

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Corneal edema is a hallmark feature of:

A

infectious canine hepatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

A Cairn Terrier is admitted to the ICU with acute abdomen. Blood glucose levels are normal. SNAPcPL is abnormal. Abdominal US shows multiple hypoechoic lesions with thickened capsule in the left pancreatic limb, measuring 2-4 cm diameter. The most likely diagnosis is:

  • Pancreatic pseudocyst
  • Insulinoma
  • Pancreatic carcinoma
  • Cysts
  • Pancreatic Abscess
  • Metastatic hemangiosarcoma
A

Pancreatic Abscess​

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

In confirming Helicobacter spp. infection of the stomach mucosa, which is the test with the best sensitivity and the quickest turn-around time?

  • Endoscopic biopsy with histopathology
  • Endoscopic biopsy and urease test
  • Urea breath test
  • Endoscopy with cytobrush for cytology
A

Endoscopy with cytobrush for cytology​

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What are two differentials for lymphocytic cholangitis in cats?

A

FIP, lymphoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

What is the most common cause of extrahepatic biliary obstruction in dogs?

A

pancreatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Only measurable and most reliable index of hepatic encephalopathy (HE):

A

ammonia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

T/F: A dog that has acute abdomen, elevated ALT and abnormal cPL (SNAP) - the definitive diagnosis is acute pancreatitis

A

False

  • The SNAP cPL has a 91% sensitivity and a 77% specificity, so a positive test should be confirmed.*
  • If negative, unlikely to have acute pancreatitis*
  • If positive, you should send away for quantitative test (Spec PLI)*
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

What is the drug of choice for treatment of large bowel IBD in the dog?

A

Sulfasalazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

A dog presents with an enlarged left anal gland ~2x size of the right. The animal does not appear to be systemically ill. How would you treat?

A

Express, lavage and infuse with topical antibiotic and steroid ointment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Which is not an end stage complication of chronic pancreatitis?

  • Pancreatic acinar atrophy (PAA)
  • Exocrine pancreatic insufficiency (EPI)
  • Diabetes mellitus
A

Pancreatic acinar atrophy PAA​

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Ultrasonographic changes of acute pancreatitis include all, except:

  • Peripancreatic hyperechogenicity
  • Pancreatic hyperechogenicity
  • Duodenal corrugation
  • Peritoneal anechoic fluid
A

Pancreatic hyperechogenicity​

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

A Doberman in Finland presents with weight loss, 2 x TN ALT, with abnormal BAS. You diagnose chronic hepatitis (CH) tentatively. What is the best course of action?

  • Start liver supportive care
  • Start prednisolone as Dobermans suffer from immune mediated CH
  • Biopsy the liver after a PT/aPTT screen
A

Biopsy the liver after a PT/aPTT screen​

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

3 month old Shar Pei. What is the diagnosis?

  • Esophageal FB
  • Spirocercosis
  • Vascular ring anomaly
  • Sliding hiatal hernia
A

Sliding hiatal hernia​

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

What are the first choice analgesics used to treat pancreatitis?

A

buprenorphine/methadone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Breeds predisposed to chronic pancreatitis include all except:

  • English Cocker Spaniel
  • Eurasier
  • Cavalier King Charles Spaniel
  • Boxer
  • Collie
A

Eurasier

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

6 month old FS dachshund. Spayed 2 weeks prior. PC: BAR but regurgitating. Most likely diagnosis?

  • Idiopathic megaesophagus
  • Vascular ring anomaly
  • Esophageal FB
  • Esophageal stricture
A

Esophageal stricture​

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

What is the treatment of choice for esophageal strictures?

A

Balloon Dilation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

T/F: The most important treatment aspect with hepatic lipidosis in cats is nutritional support

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

T/F: Trypsin‐like immunoreactivity (TLI) is very sensitive and specific for exocrine pancreatic insufficiency (EPI)

A

True

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

What drug is indicated for treatment of myasthenia gravis?

A

pyridostigmine​

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

A 4-year-old German Shepherd has body odor and perineal microabscesses on inspection. What is the mainstay of therapy for this dog?

A

Cyclosporin

This dog most likely has perianal fistula

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

Is the following clinical sign more associated with small bowel diarrhea or large bowel diarrhea:

melena

A

small bowel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

A 12 week old Boston terrier presents to your clinic with the complaint of projectile vomiting. Based on the signalment, what is the most likely diagnosis?

  • Gastric lymphoma
  • Gastric adenocarcinoma
  • Pythiosis
  • Antral pyloric stenosis
A

Antral pyloric stenosis

pyloric stenosis typically causes persistent vomiting in young animals (especially brachycephalic dogs and Siamese cats) but can be found in any animal. These animals usually vomit food shortly after eating. The vomiting is sometimes described as “projectile.” Animals are otherwise clinically normal, although some pets may lose weight.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

A 6 week old GSD presents to your clinic with vomiting. The dog is otherwise bright, alert, with a good appetite. Based on the most likely differential, what is the most appropriate diagnostic test?

  • Hematology
  • Biochemistry
  • Parvo fecal snap test
  • Thoracic radiographs
  • Echo for VSD
A

Thoracic radiographs​

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

Which is a more sensitive test: ammonia tolerance or resting ammonia?

A

ammonia tolerance

**ammonia is an encephalotoxin so must be sure that basal/resting concentrations are within resting range**

51
Q

Is the following clinical sign more associated with small bowel diarrhea or large bowel diarrhea:

mucous

A

large bowel

52
Q

T/F: Histopathology is the ONLY way to diagnose lymphocytic cholangitis

A

True

53
Q

What is the most common cause of extrahepatic biliary obstruction [EHBO] in cats?

A

tumors and inflammatory disease (FIP) of biliary tract, pancreas or both

54
Q

What breed is especially susceptible to the toxic effects of carprofen?

A

Labradors

55
Q

What is the typical treament protocol for cats with lymphocytic cholangitis?

A

prednisolone, chlorambucil, methotrexate

56
Q

This immunosuppressive agent has ~100% response rate when used in the treatment of perianal fistula:

A

Cyclosporin

57
Q

What is the most common GI neoplasia in cats?

A

lymphoma

58
Q

Is the following clinical sign more associated with small bowel diarrhea or large bowel diarrhea:

large, bulky, watery stool

A

small bowel

59
Q

Maggie, a 6-year-old, FS Shih Tzu, visits your practice for a routine health screen. She has been diagnosed with idiopathic epilepsy and is on phenobarb. She is otherwise healthy. Biochemistry detects 10 x TN ALKP, 8 x TN ALT. Which is the correct statement?

  • This is enzyme induction from phenobarbitone
  • The liver enzymes are prognostic of phenobarb damage
  • Recommend liver function testing and US/biopsy
  • Immediately discontinue phenobarb
A

Recommend liver function testing and US/biopsy

We know that phenobarbitone can be responsible for enzyme induction (specifically ALKP), but this is allowable within a certain range. Generally if ALKP is less than 5x normal, it is simple induction. However, if the enzymes are significantly elevated (as in this example), you must consider that there is phenobarbitone toxicity

60
Q

Which of the following would NOT be considered part of a therapeutic plan for perianal fistulae?

  • cyclosporine
  • tacrolimus
  • antibiotics
  • hypoallergenic diet
  • diphenoxylate
A

diphenoxylate​

diphenoxylate is a motility modifier; prolongs intestinal transit time and is principally used to symptomatically treat diarrhea

61
Q

What is the main cause of Exocrine Pancreatic Insufficiency in cats?

A

chronic pancreatitis

62
Q

T/F: If a cat presents with ptyalism, hepatic encephalopathy [HE] should be on the top of your rule-out list

A

True

63
Q

What is the “gold-standard” diagnostic modality for Tritrichomonas foetus?

A

Fecal PCR

64
Q

Treatment for chronic pancreatitis includes all except:

  • Low fat diet (ultra low fat or low residue
  • Analgesia (acetaminophen/tramadol)
  • Pancreatic supplement (for postprandial pain)
  • Antibiotic (enrofloxacin)
  • Steroids - immunosuppressive treatment
A

Antibiotic (enrofloxacin)

65
Q

A 9-year-old Persian presents to your clinic with anorexia and icterus. The abdomen is painful and the liver enlarged. Ultrasound findings are shown here. Biopsy confirms neutrophils periportal but not beyond the limiting plate. Dx?

  • Chronic lymphocytic cholangitis
  • Acute suppurative cholangitis
  • Hepatic lipidosis
  • Cholelith
A

Acute suppurative cholangitis​

66
Q

A 2 year old MN bengal cat presents with a 14 day history of green, malodorous stool, tenesmus and mucus in the stool. The cat is otherwise healthy with normal hematology and biochemistry. The previous vet treated with antibiotics and a bland diet - no response.

What is the most likely differential?

A

T. foetus

67
Q

What is the most important component of treatment in a cat with hepatic lipidosis?

A

Tube feeding!

Nutritional support is the most important component. However, you don’t want to force-feed a cat because it may develop a food aversion because cats are assholes like that and value their pride over their health.

68
Q

Quinn, a 2-year-old, MN Cockapoo in ICU is being treated for onion toxicity and has received a blood transfusion for anemia. He is now icteric. Which statement is correct regarding liver function?

  • A bile acid stim test is indicated to confirm liver dysfunction
  • An abdominal US excluding EHBO is sufficient to confirm liver dysfunction
  • There is no liver dysfunction, this is all pre-hepatic hemolysis
A

An abdominal US excluding EHBO is sufficient to confirm liver dysfunction​

69
Q

T/F: Pancreatic lipase immunoreactivity (PLI) may have the greatest diagnostic value for pancreatitis in both the dog and the cat

A

True

  • If negative PLI, unlikely to have acute pancreatitis
  • If positive PLI, you should send away for quantitative test
    • SPEC PLI is a quantitative test with 95% specificity
    • Not effected by renal failure or steroids, but very expensive
70
Q

What is the role of sucralfate in the medical treatment of esophagitis?

A

diffusion barrier to peptic mucosal damage

71
Q

Which is not a short-term prognosticator in the case of biliary mucoceles?

  • Hyperlactatemia
  • Hypotension
  • GB rupture
  • Anemia
A

GB rupture​

72
Q

T/F: ALKP is very liver-specific in the dog and cat

A

False

ALKP is very liver-specific in the CAT.

In the dog, increased ALKP could be from the intestines, kidneys, placenta, bone, drug-induced, etc.

73
Q

Bubbles, a 13-year-old English Cocker Spaniel presents with a history of recurrent AP, DM, and now chronic diarrhea with weight loss. You are concerned about end-stage EPI. What factors influence your diagnostic tests at this stage?

  • Age and comorbid DM, surgical biopsy may increase morbidity
  • Concurrent pancreatitis may affect cTLI
  • Concurrent EPI may affect cPL
  • All of the above
A

All of the above

74
Q

Is the following clinical sign more associated with small bowel diarrhea or large bowel diarrhea:

tenesmus

A

large bowel

75
Q

Which of the following factors has NOT been implicated as an etiology of acute pancreatitis?

  • Hypercalcemia
  • Corticosteroids
  • Trauma and surgery
  • Hypertriglyceridemia
  • Phenobarbitone
  • Canine babesiosis
A

Corticosteroids​

76
Q

The most common cause of EPI in the cat is:

A

chronic pancreatitis

77
Q

A 7-year-old M/N German Shepherd presents to you with a history of painful defecation. On physical exam, you note these lesions.

What is your diagnosis?

A

Perianal fistulas

78
Q

T/F: For the diagnosis of congenital PSS, fasting and postprandial serum bile acid level determinations are recommended to enhance detection ability

A

True

this is because it is relatively common for fasting values to be well within normal limits and for postprandial values to be as high as 10- to 20-fold higher than normal postprandial values.​

79
Q

When submitting a liver biopsy, what special stain would you request if you want to confirm copper accumulation?

A

rhodanine

80
Q

What is the most sensitive diagnostic test for acute pancreatitis in dogs?

A

cPL

81
Q

What signalment is associated with acute pancreatitis in dogs?

A

Usually small breed dogs; overweight, middle-aged females; history of fatty meals; post ischemia – canine babesiosis​

82
Q

What is a chronic complication of acute pancreatitis?

  • Pleural effusion
  • Hypocalcemia
  • Pseudocyst
  • Coagulopathy
A

Pseudocyst​

A pancreatic pseudocyst is a collection of fluid containing pancreatic enzymes and debris in a nonepithelialized sac. Pseudocysts have been recognized in association with pancreatitis in cats and dogs, although they appear to be rare

83
Q

Name the three disease entities involved with feline triaditis:

A

pancreatitis, cholangiohepatitis, and inflammatory bowel disease (IBD)

84
Q

T/F: Elevated amylase and lipase are diagnostic for pancreatitis in the dog

A

False

Elevated amylase and lipase are compatible with pancreatitis in the dog but are not diagnostic or pathognomonic since they can be elevated with gastrointestinal or liver disease or azotemia. And dogs with normal amylase and lipase values may have pancreatitis.

**Amylase and lipase are of no value in the cat**

85
Q

Jimmy is diagnosed with EPI, most likely from PAA. What treatments do you NOT recommend?

  • Low fat diet prescription diet
  • Cobalamin supplementation
  • Pancreatic enzyme-enteric coated
  • Metronidazole, 28 day course
  • Antacid treatment, to increase gastric pH
A

Low fat diet prescription diet​

86
Q

An icteric patient presents. Which of the following diagnostic tests is NOT indicated?

  • Bile acids
  • Packed cell volume
  • Serum biochemistry profile
  • Abdominal ultrasound
  • Urinalysis
A

Bile acids​

87
Q

You are managing a 6-month-old Yorkshire terrier with neurological signs, microcytosis, and ammonium biurate crystalluria. How would you investigate for PSS?

  • Ammonia tolerance test
  • Bile acid stim
  • Urea, Alb, Gluc
  • Liver biopsy
A

Bile acid stim

88
Q

Bobby is referred to your clinic for further investigation of liver disease. He is weak, with non-specific signs of pain. Biochemistry shows ALP (2 x TN), AST (4 x TN). What should you also test?

  • Liver enzymes: ALKP, GGT, Abdominal US
  • Muscle enzymes: CK, LDH, EMG and Toxo titres, 2M Ab assays
A

Muscle enzymes: CK, LDH, EMG and Toxo titres, 2M Ab assays​

This dog has a much higher AST than ALT, so consider the possibility that this dog has polymyositis. This demonstrates that AST and ALT are not liver-specific

89
Q

A dog presents with ptyalism, odynophagia, firm enlarged mandibular salivary glands. What is the treatment of choice?

A

Phenobarbitone​

90
Q

A 10 year old MN Pit Bull presents with shifting forelimb lameness and a history of regurgitation and odynophagia. On clinical examination you palpate enlarged mandibular salivary glands and firm thickening of the radial metaphyseal area. What is the most likely etiology?

  • Bronchoalveolar carcinoma
  • Panosteitis
  • Spirocercosis
  • Idiopathic sialadenitis
A

Spirocercosis​

91
Q

A 10-year old, MN, Golden Retriever presents to your clinic with PU/PD. Biochemistry detected a 4 x TN ALKP and mild hypoglycemia (BG 3.4 mmol/L, RI 3.5-5.5 mmol/L). Ultrasound detects the lesion shown below. What is your tentative diagnosis?

  • Lymphoma
  • Hepatocellular carcinoma
  • Hemangiosarcoma
  • Biliary cystadenoma
A

Hepatocellular carcinoma​

92
Q

What is the most common hematologic finding in dogs with severe pancreatitis?

A

neutrophilia with a left shift ​

93
Q

Trigger, a 5 year old intact male GSD presents to your clinic for a primary complaint of weight loss. The owners report his appetite is great although his bowel movements smell horrible. On exam, you note he is BAR, has a poor hair coat and BCS = 1.5/5. What is your tentative dx?

  • EPI
  • Pancreatitis
  • Insulinoma
  • Acute hepatitis
A

EPI​

94
Q

When submitting a liver biopsy, what special stain would you request if you want to confirm amyloid accumulation?

A

congo red

95
Q

A 1-year-old male labrador from Alabama has a history of projectile vomiting. You ultrasound the abdomen and find this abnormality at the pylorus cross-section. Considering the signalment and history, what is the tentative diagnosis?

  • Acquired antral pyloric hyperplasia
  • Congenital pyloric stenosis
  • Pythiosis
  • Intussusception
A

Pythiosis​

96
Q

The most accurate blood test for diagnosing pancreatitis in cats:

A

Feline Spec PL

97
Q

What is the role of metoclopramide in the medical treatment of esophagitis?

A

to improve tone of caudal esophageal sphincter​

98
Q

An otherwise healthy 4-year-old border collie. PC: regurgitation. What is your diagnosis?

  • Vascular ring anomaly
  • Sliding hiatal hernia
  • Idiopathic megaesophagus
  • Esophageal FB
A

Idiopathic megaesophagus

99
Q

Silkworm, a 2 year-old overweight, MN, DSH is presented to your clinic for anorexia. Biochemistry tests detect 2 x TN ALKP. Which interpretation is correct?

  • ALKP has many isoenzymes. This is not liver specific
  • ALKP is liver specific for the cat and Silkworm has hepatic lipidosis
  • Increased ALKP is not significant, due to the long half-life and it is ‘too sensitive’
A

ALKP is liver specific for the cat and Silkworm has hepatic lipidosis​

100
Q

Do we see abdominal contractions in vomiting or regurgitation?

A

Vomiting!

  • Vomiting is associated with abdominal contractions!*
  • Regurgitation is a passive process.*
101
Q

Current feeding recommendations indicate enteral or partial parenteral nutrition as soon as vomiting is under control. What diet should be fed?

  • Intestinal bland diet
  • Hypoallergenic diet
  • Novel protein diet
  • Low fat diet
A

Low fat diet​

102
Q

Midge, a 4-year-old Fox terrier has weight loss, mild hypoalbuminemia. There is microhepatica. How would you confirm liver failure?

  • Bile acid stim
  • Ammonia tolerance test
  • Low albumin, urea, glucose
  • Prolonged PT/aPTT
A

Ammonia tolerance test​

103
Q

The most specific marker of liver function:

A

Bile Acids Stimulation Test

**Not helpful in hepatic/post hepatic jaundice**

104
Q

What is the treatment protocol for feline suppurative cholangitis?

A

Broad-spectrum antibiotics (Clavamox & cephalosporins)

Also supportive care, vitamin K, SAMe, UDCA

105
Q

Which of the following is FALSE about chronic liver disease?

  • No improvement after 6 months or longer
  • Progresses to fibrosis and cirrhosis
  • Cause is often indicated from bacteria or viruses
  • Copper accumulation can cause chronic liver disease
A

Cause is often indicated from bacteria or viruses​

106
Q

Which is the parameter associated with the worst outcome (prognosticator) in CH?

  • Normal liver enzymes
  • Copper concentration > 1500
  • Ascites with hypoalbuminemia
  • Prolonged PT/aPTT
A

Prolonged PT/aPTT​

107
Q

Enteral nutrition for cats with HL should be supplemented with which essential amino acid (11) to assist mitochondrial fatty acid oxidation?

  • L-carnitine
  • Arginine
  • Taurine
  • Methionine
A

L-carnitine

108
Q

You are asking an owner about the incidence of vomiting in their dog. They describe it as happening quickly after eating and it is often undigested food.

Do you think this is vomiting or regurgitation?

A

Regurgitation

109
Q

On ultrasound, you note retrograde dilatation of the common bile duct and gall bladder and tortuous common bile duct. What is your diagnosis?

A

Extrahepatic Biliary Obstruction [EHBO]

110
Q

Increased ammonia is not seen until more than ___% hepatic capacity is lost

A

70%

Increased ammonia is not seen until more than _70%_ hepatic capacity is lost

111
Q

In the majority of cases of acute liver failure, how does the liver appear on ultrasound?

A

diffusely hypoechoic

112
Q

Diagnosis?

A

persistent right aortic arch (PRAA)

113
Q

What is not a result of acute pancreatitis?

  • Local inflammation and necrosis
  • Cytokine storm
  • SIRS
  • Loss of endocrine and exocrine function
  • Systemic dissemination of activated enzymes
A

Loss of endocrine and exocrine function​

Loss of endocrine and exocrine function happens with chronic pancreatitis​

114
Q

T/F: Hypoglycemia is uncommon in dogs

A

True

Most commonly seen associated with shunts, fulminant failure, young/small dogs

115
Q

The most common form of pancreatitis in dogs is:

  • Acute pancreatitis
  • Chronic pancreatitis
  • Acute on chronic
A

Acute on chronic

116
Q

What is the diagnostic modality of choice for Extrahepatic Biliary Obstruction [EHBO]?

A

Ultrasound!

sediment, choleliths, wall thickeneing, EHBO, emphysema of the wall, pericholecystic fluid

117
Q

What are the two leading complications associated with biliary mucoceles?

A

hyperadrenocorticism and hyperlipidemia

Additional risk factors:

  • Breed: Shetland sheepdog (PC def), mixed breed, Bichon frise, Miniature and toy poodles, West Highland white terriers, Dachshund, German shepherd and Cocker spaniel
  • Age: 11 years (3‐17) with no gender over represented
  • Endocrinopathies: hyperadrenocorticism (21%), diabetes mellitus (6%), hypothyroidism (12%)
  • Pancreatitis (12%)
  • Gallbladder dysmotility (10%)
  • High fat diet (10%)
  • PLN (6%)
  • Gallbladder neoplasia (5%)
  • Hyperlipidaemia (21%)
118
Q

T/F: Surgery is the definitive treatment for biliary mucoceles

A

True

  • You are not likely to have much luck if you try to medically manage these patients!*
  • And remember, whenever you remove a gallbladder, the most important thing for you to do is to ensure patency of the common bile duct!!*
119
Q

Pain or difficulty in swallowing is termed:

A

dysphagia

120
Q

Tilly, a 7 year old FS Chinese crested presents to you with this mass under the chin. It is soft and painless on palpation and does not seem to be attached to any underlying tissues. Diagnosis?

  • Sialadenitis
  • Sialocele
  • Thyroid carcinoma
  • Pharyngeal stick injury
A

Sialocele​

121
Q

How do you confirm sialocele?

A

“drip-test”

aspirate honey-coloured tenacious fluid

122
Q

A dog presents with chronic small intestinal diarrhea and you suspect the cause is parasitic. The owner has some financial constraints, so you recommend a 5-day course of ___________

A

fenbendazole

123
Q

What is the most common pancreatic neoplasia in cats?

A

adenocarcinoma

124
Q

___________ is most common tumor affecting pleural space

A

mesothelioma

Mesothelioma is most common tumor affecting pleural space. Laparoscopy or laparotomy is typically required to make a definitive diagnosis.