Salmonella Typhi Flashcards
1
Q
Describe the microscopic appearance of salmonella typhi
A
Gram negative - pink
Rods
2
Q
How is salmonella typhi spread?
A
Oral-faecally
3
Q
Where is the site salmonella typhi infects?
A
Peyers patches (macrophages of intestinal lymph)
4
Q
Describe the virulence factors for salmonella typhi
A
Produces endotoxin that causes encephalopathy, myocarditis and intravascular coagulation
5
Q
What are the consequences of infection with salmonella typhi?
A
Typhoid fever - intestinal perforation and haemorrhage, encephalopathy, myocarditis, intravascular coagulation
6
Q
How does infection with salmonella typhi present?
A
Fever
Maculopapular rash on trunk
Bloody diarrhoea
7
Q
How is salmonella typhi treated?
A
Prevent with vaccine
Treat with ceftriaxone
