Neisseria Meningitidis Flashcards
1
Q
Describe the typical presentation of a neisseria meningitidis infection
A
Fever Malaise Joint pain Rigid neck Vomiting Photosensitivity Purpuric rash
2
Q
Describe the virulence factors for neisseria meningitidis
A
Capsule - antiphagocytotic
Produces IgA protease - evades immunoglobulins
Produces toxins - induces shock
3
Q
Describe the appearance of neisseria meningitidis under a microscope
A
Gram negative - pink
Diplicoccus
4
Q
What are the consequences of neisseria meningitidis infection?
A
Infected meninges causing acute inflammatory response, raised ICP
Septicaemia and shock, causing circulatory collapse
5
Q
How does neisseria meningitidis cause infection?
A
Droplet infection from carrier
In carrier, travels from nasopharynx to blood stream
6
Q
How is neisseria meningitidis treated?
A
Penicillin