Salivary Glands - Pathoma Flashcards
What major gland does the Mumps virus effect?
Results in bilateral inflamed parotid glands
What additional conditions are associated with the Mumps virus?
- Orchitis - inflammation of the testicles
- risk of sterility
- >10yoa => worried about teenagers
- Pancreatitis
- Aseptic meningitis
What enzyme is increased due to Mumps viral involvement of the salivary gland or pancreas?
Serum amylase
What is Sialadenitis?
Inflammation of the salivary gland
What is Sialadenitis most commonly due to?
Obstructing stone (sialolithiasis) leading to S. Aureus infection
Is Sialadenitis usually bilateral or unilateral?
Usually unilateral
What is the most common benign tumor of the salivary gland?
Pleomorphic Adenoma
What tissue types is a Pleomorphic Adenoma composed of?
Benign tumor composed of stromal (e.g. Cartilage) and epithelial tissue (e.g. Glands)
What major gland does a Pleomorphic Adenoma usually arise in?
Parotid gland
How do patient’s with a Pleomorphic Adenoma present?
With mobile, painless, circumscribed mass at the angle of the jaw.
Why is there a high rate of recurrence of Pleomorphic Adenoma?
***IRREGULAR MARGINS!!!
-Extensions of small islands of tumor through tumor capsule often results in incomplete resection.
Can a Pleomorphic Adenoma turn into Carcinoma? How would it present?
Rarely transforms into carcinoma.
Presents with signs of facial nerve damage.
What is a Warthin Tumor?
Benign cystic tumor with abundant lymphocytes and germinal centers
TAKE HOME: “Cystic tumor with lymphoid tissue”
What is the second most common tumor of the salivary gland?
Warthin Tumor
What major gland does a Warthin Tumor arise in?
Almost always arises in the parotid gland.
