Salivary Gland Development Flashcards
1
Q
What is mucin?
A
Proteins (glycoproteins) in saliva for lubrication
2
Q
Caspase-3 is an important signal for what?
A
Apoptosis
3
Q
What are signals important in the canalicular stage?
A
Caspase-3, survivin, Shh/Ptc, EDA/EDAR
4
Q
Salivary glands are derived from what origin?
A
ECTODERMAL
5
Q
What are the stages of salivary gland development?
A
Prebud
Initial bud
Pseudoglandular
Canalicular
Terminal bud
6
Q
What signals are needed for proper gland development?
A
FGF2
FGF10
EDAR
7
Q
Developing glands separate into epithelium and mesenchyme. After how many days do they come back together to make a proper gland?
A
13.5 days
8
Q
If you combined the pre-bud and salivary mesenchyme, would we get a salivary gland?
A
NO
9
Q
What NT is needed for proper salivary gland development?
A
Acetylcholine
