Salivary Gland Development

Question 1

What is mucin?

Answer 1

Proteins (glycoproteins) in saliva for lubrication

Question 2

Caspase-3 is an important signal for what?

Answer 2

Apoptosis

Question 3

What are signals important in the canalicular stage?

Answer 3

Caspase-3, survivin, Shh/Ptc, EDA/EDAR

Question 4

Salivary glands are derived from what origin?

Answer 4

ECTODERMAL

Question 5

What are the stages of salivary gland development?

Answer 5

Prebud

Initial bud

Pseudoglandular

Canalicular

Terminal bud

Question 6

What signals are needed for proper gland development?

Answer 6

FGF2

FGF10

EDAR

Question 7

Developing glands separate into epithelium and mesenchyme. After how many days do they come back together to make a proper gland?

Answer 7

13.5 days

Question 8

If you combined the pre-bud and salivary mesenchyme, would we get a salivary gland?

Answer 8

NO

Question 9

What NT is needed for proper salivary gland development?

Answer 9

Acetylcholine