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Oral Biology - Quiz 3 > Dentin Pulp Complex II > Flashcards

Dentin Pulp Complex II Flashcards

1
Q

What is the endgame of dentistry?

A

KEEP THE PULP HAPPY

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2
Q

What is the dental pulp?

A

Living, highly cellular core of the tooth

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3
Q

What is the primary cell type of the pulp?

A

Fibroblasts
—Maintain pulp matrix

*Next most numerous are the odontoblasts

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4
Q

The dental pulp arises from>

A

ECTOMESENCHYMAL

—Dental papilla

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5
Q

What does the pulp do>

A

Support the mineralized components of the tooth

Includes:

  • Blood vessels
  • Innervation
  • Fibroblasts
  • Immune cells
  • Progenitor cells for replacement and repair
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6
Q

What are the 4 histological zones of the pulp from outer to inner?

A

OD Layer

Cell FREE Zone of Weil

Cell RICH Zone

Pulp Core

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7
Q

The extracellular matrix of the dental pulp is comprised of 2/3rds what and 1/3rd what?

A

2/3rds - Collagen III

1/3rd - Collagen I

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8
Q

T/F - With age, collagen content increases, and fibrils aggregate into larger bundles, with the greatest concentration apically.

A

TRUE

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9
Q

The ground substance of the pulp is made of what 3 things?

A

Proteoglycans

Glycoproteins

Water

*On a non-mineralized collagen matrix

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10
Q

What are odontoblasts (ODs)?

A

POLARIZED cells

Elongated nucleus at the pulpal side of cell

Secretory components (Golgi bodies)
—Toward the dentinal side
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11
Q

ODs form a layer of cells held together by what?

A

Junctional complexes

ADHERANS JUNCTIONS, NOT ZONULAR

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12
Q

ODs can form gap junctions with what?

A

Pulpal fibroblasts

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13
Q

Fx of ODs?

A

Creation and maintenance of dentin

Supported by the rest of the pulp

Collagen and non-collagenous protein production and secretion

Key growth factors

Vesicular release from the OD process forms peritubular dentin

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14
Q

T/F - Tertiary dentin has NO tubules.

A

TRUE

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15
Q

What do fibroblasts do?

A

Support odontoblasts and help to hold things in place

Produce and maintain the supportive matrix of the pulpal tissue

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16
Q

Where are fibroblasts found?

A

Pulp core and cell rich zone

17
Q

What are the dental pulp progenitor cells?

A

Mesenchymal progenitor cells present in the pulp

They are recruited to form new odontoblast-like cells in response to the dentin
—Involved in reparative dentin formation

18
Q

Tell me about the immune cells in the pulp.

A

Macrophages

IL-1beta, TNFalpha

Dendritic cells

19
Q

What is the vascular supply to the pulp?

A

Arise from external carotid aa and sup/inf alveolar aa

20
Q

T/F - 4-8 arterioles/root access the pulp thru the apical foramen.

A

TRUE

Progression: Arterioles, capillaries, venules

Capillaries present in the cell free zone

21
Q

Tell me about the lymphatic supply to the dental pulp.

A

Drain vascular exudate, and interstitial fluid out of the pulp

  • Lymph flow is equal to arterial interstitial flow
  • Lymphatic vessels have thinner walls, epithelial lining, and thin smooth muscle layer
22
Q

T/F - The pulp is highly innervated by nerve (nociceptive nerve endings).

A

TRUE

23
Q

T/F - Nerve fibers branch out thru the coronal pulp, forming the PLEXUS OF RASCHKOW.

A

TRUE

24
Q

In the root pulp, are there plexuses of RASCHKOW?

A

No

-Branches of nerve fibers

25
Q

Incoming nerve fibers consist of afferent nerves from the _________, and sympathetic branches from the ______ _______ ________.

A

Trigeminal

Superior cervical ganglion

26
Q

Nerve bundles consist of what 2 types of axons?

A

Alpha-delta - myelinated

C - unmyelinated

27
Q

T/F - Myelination decreases as fibers proceed toward the coronal pulp.

A

TRUE

28
Q

T/F - Some unmyelinated nerves pass into the tubules and are closely associated with odontoblasts.

A

TRUE

29
Q

Walk me thru the chart on slide 17.

A 
Infection/breakdown of matrix
-Vasculature, immune cells, nerves
—Progenitor cells
—-Fibroblasts
—-Odontoblasts

Fibroblasts lead to pulp matrix repair
Odontoblasts lead to tertiary dentin

30
Q

What are the 3 models of dentin sensitivity?

A

Direct innervation

Odontoblast nociception

Tubule fluid conductance

31
Q

What are pulp stones?

A

Mineralized tissue formed inappropriately in the pulp

-True
—Tubules and OD-like cells (rare)

-False
—Atubular mineralized tissue, sometimes with necrotic tissues at the center

32
Q

Why does the pulp recede as we grow older?

A

Secondary dentin formation

-Reduction in cell number

33
Q

Tell me more about age related changes in pulp.

A

Decrease in pulp permeability (peritubular occlusion), but more brittle teeth

Loss of nerve axons, decrease in sensitivity

Oral Biology - Quiz 3 (7 decks)

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