SA Exocrine Pancreas

Question 1

What is the pathogenesis of acute pancreatitis?

Answer 1

Idiopathic autolysis and trypsin release - sterile inflammation

Question 2

What are the most common clinical signs of pancreatitis?

Answer 2

Lethargy, dehydration, anorexia, vomiting, abdominal pain

Question 3

What other inflammatory processes may pancreatitis be associated with in the cat?

Answer 3

Enteritis and cholangitis

Question 4

What biochemical changes occur with pancreatitis?

Answer 4

Increased lipase, amylase, pancreatic lipase (Total lipase just as good)

Question 5

How can pancreatitis be treated?

Answer 5

Nutritional support - reduce food intake, fluid therapy, analgesia, SBI antibiotics, feed PO once vomiting stops

Question 6

What types of analgesics should be used with cases of pancreatitis?

Answer 6

NOT NSAIDS

Opioids - fentanyl, ketamine, hydromorphone,

Question 7

What pathology is associated with EPI in dogs?

Answer 7

Young - pancreatic atrophy/ hypoplasia

Old - chronic pancreatitis

Question 8

What clinical signs are associated with EPI?

Answer 8

Steatorrhoea, polyphagia, coprophagia, poor condition/ coat, vomiting

Question 9

What test gives a definitive EPI diagnosis?

Answer 9

Faecal elastase, TLI

Question 10

What dietary management should be employed for animals with EPI?

Answer 10

Feed highly digestible diets !!

Question 11

What substance in the body is a prognostic indicator of EPI?

Answer 11

Cobalamin

Question 12

DGGR lipase

Answer 12

Correlated with pancreatitis

Question 13

SPLI

Answer 13

Snap test - more sensitive than lipase or amylase