S3_L1: Introduction to Osteoarthritis and Rheumatoid Arthritis Flashcards
TRUE OR FALSE: Synovial joints are the most common type of joint found in the human body. Only synovial (true) joints will have an arthritis.
A. Both statements are true
B. Both statements are false
C. Only the 1st statement is true
D. Only the 2nd statement is true
A. Both statements are true
Synovial joints are characterized by the presence of a fluid-filled (1)_______ contained within a (2)_______
- joint cavity
- fibrous capsule
Synovial joints are covered by a thin layer of ________
hyaline cartilage
The following statements are true about the Articular Capsule, EXCEPT:
A. connective tissue surrounds the bone
B. connects one bone to another
C. continuous with the periosteum of articulating bones
D. consist of the fibrous and synovial layer
E. None of the above
A. connective tissue surrounds the bone
NOTE: It surrounds the joint
Match the following layers of the articular capsule to its corresponding description.
- highly vascularized
- holds together the articulating bones
- absorbs and secretes synovial fluid
- blends with ligaments
- AKA as the synovium
A. Fibrous layer
B. Synovial layer
- B
- A
- B
- A
- B
What do you call the white fibrous tissue that makes up the fibrous layer of the articular capsule?
capsular ligament
Enumerate the three main features of a synovial joint.
- articular capsule
- articular cartilage
- synovial fluid
What is the main function of the fibrous layer?
Support
Match the following cell types found in the synovial layer.
- produce synovial fluid
- unknown function and origin
- located in superficial layer
- derived from macrophages
- intermediate cell type
A. type A cells
B. type B cells
C. type C cells
- B
- C
- A
- A
- C
Match the following cell types found in the synovial layer.
- has a phagocytic function
- non-fixed cells with antigen presenting ability
- fibroblast like cells
- serve as multipotent precursor
- produce hyaluronic acid, fibronectin, collagen
A. type A cells
B. type B cells
C. type C cells
- A
- A
- B
- C
- B
TRUE OR FALSE: The main function of the synovial layer is to mediate nutrient exchange between blood and joint fluid
True
The synovial fluid (1)_____ the articular cartilage and provides (2)______ through (3)_____
- lubricates
- nourishment
- diffusion
Synovial fluid is made from an ultrafiltrate of ____
blood plasma
The Synovial fluid consists the following, EXCEPT:
A. hyaluronic acid
B. prostaglandins
C. leukotrienes
D. collagenases
E. None
C. leukotrienes
Determine which content of the synovial fluid is being described.
Reduces friction between opposing surfaces of cartilage
A. hyaluronic acid
B. prostaglandins
C. lubricin
D. collagenases
E. proteinase
C. lubricin
Determine which content of the synovial fluid is being described.
Lubricate the surface between synovium and cartilage
A. hyaluronic acid
B. prostaglandins
C. lubricin
D. collagenases
E. proteinase
A. hyaluronic acid
Determine which content of the synovial fluid is being described.
Increase the viscosity and elasticity of articular cartilage
A. hyaluronic acid
B. prostaglandins
C. lubricin
D. collagenases
E. proteinase
A. hyaluronic acid
Determine which content of the synovial fluid is being described.
Responsible for the boundary layer lubrication
A. hyaluronic acid
B. prostaglandins
C. lubricin
D. collagenases
E. proteinase
C. lubricin
The articular cartilage (Hyaline) has two main roles:
- minimizes ______ upon joint movement
- absorbs _______
- friction
- shock/load
The following are functions of the synovial fluid, EXCEPT:
A. Lubrication
B. Friction Minimization
C. Shock absorption
D. Nutrient distribution
E. None
B. Friction Minimization
Articular cartilage is relatively (1)_____, and is reliant upon the passive (2)_____ of nutrients from the synovial fluid.
- avascular
- diffusion
TRUE OR FALSE: Accessory Ligaments consist of bundles of thin irregular connective tissue. It highly adapted for resisting shock.
A. Both statements are true
B. Both statements are false
C. Only the 1st statement is true
D. Only the 2nd statement is true
B. Both statements are false
NOTE: These are dense regular connective tissue, highly adapted for resisting strain.
This is a a small sac lined by synovial membrane, and filled with synovial fluid.
Bursae
TRUE OR FALSE: Bursae afford joints greater freedom of movement, whilst protecting the articular surfaces from friction induced degeneration
True
A bursa can become inflamed following (1)_____ or (2)_____ of the joint
- infection
- irritation by overuse
This law states that the nerves supplying a joint also supply the muscles moving the joint and the skin covering their distal attachments
Hilton’s Law
This is a joint disorder featuring inflammation is frequently accompanied by pain.
Arthritis
Joint pain is referred to as _______
arthralgia
Arthritis leads to the following impairments, EXCEPT:
A. Chronic pain
B. Loss of function
C. Deformities
D. Decrease in overall QOL
E. None
E. None
TRUE OR FALSE: Arthritis is the most common cause of disability
True
The following characterizes an articular arthritis, EXCEPT:
A. “locking”
B. crepitation
C. instability
D. hypermobility
E. None
D. hypermobility
What kind of pain characterizes an articular arthritis?
deep or diffuse pain
The following characterizes a NON-articular arthritis, EXCEPT:
A. pain on active ROM
B. pain on passive ROM
C. focal tenderness adjacent to articular structures
D. crepitus
E. None
B. pain on passive ROM
Enumerate the four cardinal signs of inflammation
Erythema (rubor)
Warmth (calor)
Pain (dolor)
Swelling (tumor)
What is the 5th cardinal sign of inflammation?
loss of function
The following are signs and symptoms of inflammatory disorders, EXCEPT:
A. Endocrinopathy
B. Cardiac failure
C. Depression
D. Anemia
E. None
E. None
The following are signs and symptoms of inflammatory disorders, EXCEPT:
A. Evening stiffness
B. Fever
C. Rash
D. Weight loss
E. None
A. Evening stiffness
The following are signs and symptoms of inflammatory disorders, EXCEPT:
A. hyperalbuminemia
B. thrombocytosis
C. fatigue
D. poor nutrition
E. None
A. hyperalbuminemia
Determine if the following is an inflammatory disorder or not.
- Neoplasm
- Pseudogout
- Fibromyalgia
- Reiter’s syndrome
- Systemic lupus erythematosus
A. Inflammatory disorders
B. Non-inflammatory disorders
- B
- A
- B
- A
- A
The following is true about the s/sx of non-inflammatory disorders, EXCEPT:
A. intermittent stiffness
B. gel phenomena
C. morning stiffness
D. pain without synovial swelling or warmth
E. None
C. morning stiffness
TRUE OR FALSE: Non-inflammatory disorders have intermittent stiffness that is is precipitated by brief periods of rest, usually lasts <60 min, and is exacerbated by activity
True
Determine in which category is a disease frequently occurs more.
- RA
- SLE
- Fibromyalgia
- Gout
- Spondyloarthropathies
A. Male
B. Female
- B
- B
- B
- A
- A
Determine in which category is a disease frequently occurs more.
- Sarcoidosis
- Polymyalgia rheumatica
- SLE
- Giant cell arteritis
- Wegener’s granulomatosis
A. Whites
B. Black
- B
- A
- B
- A
- A
Determine in which category is a disease frequently occurs more.
- OA
- RA
- Psoriatic arthritis
- Fibromyalgia
- SLE
A. Children
B. Young adults
C. Middle Age
D. Elderly
- D
- C
- A
- C
- B
Determine the onset of the following diseases.
- OA
- RA
- septic
- fibromyalgia
- gout
A. Abrupt
B. Insidious
- B
- B
- A
- B
- A
Determine the evolution of the following diseases.
- OA
- Lyme arthritis
- Viral arthritis
A. Chronic
B. Intermittent
C. Migratory
D. Additive
- A
- B
- C
Determine the evolution of the following diseases.
- RA
- Rheumatic fever
- Psoriatic arthritis
A. Chronic
B. Intermittent
C. Migratory
D. Additive
- D
- C
- D
Determine the duration of the following diseases.
- infectious
- RA
- reactive
- fibromyalgia
- crystal induced
A. Acute
B. Chronic
- A
- B
- A
- B
- A
An acute duration for arthritis is _____ weeks
less than 6
Articular disorders are classified based on the number of _____ involved
joints
How many joints are involved when the term oligoarticular or pauciarticular is used?
2 or 3