S3: Introduction to Sensory Physiology and Perception Flashcards
Describe the basic pathway of transmission of a stimulus
- First there is an external event - usually external to the body but can be within the body e.g. interoceptors.
- This stimulates a sensory receptor cell e.g. light stimulating retina or pressure on skin.
- The sensory receptor needs to both detect the stimulus and convert it into electrical potential (transduce it). This is the stimulation being transduced into a change in the membrane potential called a receptor potential.
- If the depolarisation succeeds in getting the afferent up to threshold, an action potential will occur and information will propagate up to the CNS via a primary afferent.
What are the three main things the CNS does/uses with information from a sensory stimulus?
- Subconscious.
- Sensation and Perception.
- Arousal.
Describe subconscious processes the CNS initiates
- Control of movement like proprioceptor and vestibular input to the motor pathways.
- Autonomic responses, for example, olefactory input stimulating salivation and increased gastric motility.
- Behavioural responses for example sight or smell of food promotes feeding behaviour (feeling of hunger).
Describe arousal processes (sleep, wakefulness and attention) the CNS initiates
Modulatory pathways control the sleep/wake cycle and these pathways choose which of the stimuli we are aware of and attend to. They do not just control sensory pathways but are also affected by them:
- Sleep and wakefulness where sensory input can wake a person from sleep, sensory deprivation can induce sleep.
- Focusing attention where you concentration on one sensory thing which suppresses awareness of others.
- Switching attention where a salient (more important) stimulus can recapture awareness away from original one.
What is sensory and perception?
Sensory is the awareness that an event as occurred. Perception is the ability to process and understand the information i.e. what it is, where it is, what does it mean, what should I do?
What does somatosensory mean?
Somatosensory refers to sensation that can occur anywhere in the body rather than just at a single sense organ e.g. sight, taste.
List and describe receptors that detect the stimulus
- Photoreceptors can detect light (electromagnetic radiation) giving vision.
- Chemoreceptors can detect chemicals in the air giving smell, chemicals in saliva giving taste and inflammatory chemicals during injury.
- Thermoreceptors detect temperature like heat, cold and injury.
- Mechanoreceptors detect pressure in skin with touch and injury, detect pressure/tension/stretch in musculoskeletal system allowing proprioception, can detect head movement and gravity to give us our sense of equilibrium and can detect sound through pressure waves in the air giving us our sense of hearing.
List somatosensory stimulations
- Inflammatory chemicals from injury.
- Temperature.
- Pressure on the skin e.g. touch receptors and injury receptors.
- Pressure/tension/stretch in musculoskeletal system for proprioception.
What are somatosensory receptors the same as?
Somatosensory receptors are also primary afferents (somatosensory afferent).
Describe structure of primary afferent in touch sensory system (combined receptor and afferent)
- The primary afferent consists of pressure sensitive endings and afferent axon. The somatosensory receptor is a continuation of the axon so they are the same and this is also seen in the olfactory system. Normally other sensory systems have seperate receptor and afferent.
- At the end of the afferent, there is fine aborisation (branching structure at end of nerve fibre) in the skin and this is where the sensitive membrane is found. The sensitive membrane is part of the distal aborisation of an axon that runs into the dorsal root and up into the brainstem. The axon therefore runs from end of finger to brain stem.
Describe how somatosensory receptors are resilient to injury
- The afferents are going to our skin and every time we cut our finger we cut them.
- However, the lose nerve endings can regrow and it should grow back in the same place restoring sensation.
- Axons can also grow into transplanted tissue and grow nerve endings.
Give examples of systems with receptors as seperate cells to the afferents
- Visual systems
- Auditory and vestibular systems
- Gustatory system
Why do most sensory systems have receptors seperate to afferents?
With combined receptor and afferent, the type of sensation they are detecting is quite primitive, achieved simply by a few proteins in the membrane.
For most our sensory system, more complex receptors are required such as visual, auditory, taste and equilibrium where the receptors are separate specialised cells. They can’t just grow an axon as they are too specialised. These cells communicate with afferents via excitatory synapses .
Describe structure of sensory receptors as seperate cells
- Receptors are separated from axon by excitatory synapse.
- The separate cells will produce receptor potentials in response to stimulus. This causes a release of glutamate that will bind to the post synaptic afferent and cause an excitatory post synaptic potential that may also produce an action potential.
What is action potential threshold?
Membrane potential at which action potentials are triggered. This is a function of the vgNa+ channel and can be treated as a constant.