RSI Pharmacology Flashcards
Common RSI Premeds
Atropine, Fentanyl
Atropine use, dose, onset
Prevent bradycardia in peds <1 year old, 0.02mg/kg, 2-4 min.
Fentanyl use dose onset
For intubating patients with increased ICP, 1-3mcg/kg, 1-3min
Common push dose pressors
Epi, Vasopressin, Neosynephrine
Push dose Epi use, dose, onset
MAP<65 unrelated to trauma, 5-20mcg, q1-5
Vasopressin use, dose, onset
MAP<65, 2units q 2min
Neosynephrine use, dose, onset
MAP<65, 50-200mcg q 1-5
Shock Index Calculation
PR/SBP; SI>0.9 = High Shock Index
8Ps
Preparation Positioning Preoxygenate Pretreat Paralysis and Induction Protection and Positioning Placement and Proof Post Intubation Management
HEAVEN
Hypoxemia-DL Extremes of Size-VL Anatomic Disruption-VL Vomits, Blood, Fluids-DL/VL + SALAD Exsanguination-DL Neck Mobility-VL
Common Sedatives
Ketamine, Etomidate
Ketamine use, dose, duration, contraindications
RSI w/ high shock index or acute bronchospasm and pediatrics
1-2mg/kg
30min
HTN
Etomidate use, dose, onset, duration, contraindications
RSI with HTN 0.3mg/kg 15-45sec 3-12min Renal insufficiency due to sepsis, hypotension
Common Paralyzing Agents
Succinylcholine, Rocuronium, Vecuronium, Nimbex
Succinylcholine use, dose, onset, duration, contraindications
Depolarizing agent for RSI (IDEAL) 1.5-2mg/kg 30-60sec 4-10min Hyperkalemia, non acute SCI, Crush injury, or burn
Rocuronium use, dose, onset, duration
Non-depolarizing agent for RSI
0.6-1.2mg/kg
55-70sec
30-60min
Tube sizing for adult males
8.0-9.0
Tube sizing for adult females
7.0-8.0
Tube sizing for peds > 1 year
(Age + 16)/4
Tube placement depth at teeth
3x ETT size
Traditional Initial Vent Settings (Vt, RR, I:E, PEEP, FiO2)
8ml/kg 10-12/min 1:2 5cm H2O 100%
Lung Protective Initial Vent Settings (Vt, RR, I:E, PEEP, FiO2)
6ml/kg 12-20/min 1:2 2-15cm H2O 100%
Obstructive Initial Vent Settings (Vt, RR, I:E, PEEP, FiO2)
6ml/kg 5-8/min 1:4 0-5cm H2O 100%
Hypovolemic Initial Vent Settings (Vt, RR, I:E, PEEP, FiO2)
8ml/kg 10-12/min 1:2 0-5cm H2O 100%
Common Post Induction Sedatives
Ketamine, Midazolam, Lorazepam
Ketamine Post Induction dose
0.5-1 mg/kg q 10min
Midazolam Post Induction dose
2.5-5mg q3-5 min
Lorazepam Post Induction Dose
1-2mg q 15min
Rocuronium Post Induction Dose
1mg/kg
Ideal Body Weight formula
(2. 3 x Height greater that 60”) + 50kg for males
(2. 3 x Height greater that 60”) + 45.5kg for females
Target Minute Volume
100mL/kg/min
Target RR
Minute Volume/ Tidal Volume
Target Tidal Volume
6-8mL/kg