Oxygenation Physiology Flashcards

1
Q

V/Q mismatch definition

A

Ventilation / Cardiac output mismatch

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2
Q

Perfusion equation

A

DO2 = Q x CaO2 Perfusion equals cardiac output x content of arterial oxygen

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3
Q

Process of glycolysis

A

Glucose is converted into two pyruvate molecules

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4
Q

Total ATP production of Krebs cycle

A

38 ATP

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5
Q

Name the three stages of metabolism in order

A

Glycolysis, Citric acid cycle, Oxidative Phosphorylation

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6
Q

Name the three Ps of Hypocapnia

A

Pulse, Perfusion, pH

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7
Q

Formula for calculating MAP

A

(SBP + (2 x DBP)) / 3

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8
Q

Definition of PaO2

A

Partial pressure of arterial oxygen

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9
Q

Definition of PO2

A

Partial pressure of environmental oxygen

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10
Q

Definition of PAO2

A

Partial pressure of alveolar oxygen

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11
Q

Definition of SaO2

A

Saturation of arterial oxygen

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12
Q

Definition of SpO2

A

Saturation of bound hemoglobin

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13
Q

Definition of SvO2

A

Venous oxygen saturation (pulmonary artery catheter)

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14
Q

Definition of ScvO2

A

Central venous oxygen saturation (central line catheter = 5-8% higher than SvO2)

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15
Q

Definition of CaO2

A

Content of arterial oxygen

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16
Q

Definition of DO2

A

Delivery of oxygen

17
Q

Carrying capacity of hemoglobin for oxygen

A

1.34 mL

18
Q

Typical cardiac output for an adult

A

5L / min

19
Q

Typical BSA for an adult

A

1.7 m2

20
Q

Definition of Fick Formula

A

Cellular uptake of oxygen

21
Q

List the four identifiable causes of hypoxia

A

Hypoxic, hypemic, stagnant, histotoxic

22
Q

Relationship between EtCO2 and PaCO2

A

PaCO2 is higher by 2-3 points

23
Q

Relationship between SpO2 and PaO2

A

SpO2 is higher by 30 points

24
Q

Name of the effect that causes a rightward shift of the OHDC

A

Bohr effect

25
Q

Factors that cause a rightward shift of the OHDC

A

Raised acid, raised CO2, raised temp, raised 2-3 DPG, raised PaO2

26
Q

Define Haldane effect

A

Hemoglobin’s ability to offload oxygen is directly proportional to acid levels and concentration of CO2

27
Q

Name of the effect that causes a leftward shift of the OHDC

A

Haldane effect

28
Q

Factors the cause a leftward shift of the OHDC

A

Low temp, low acid, low 2-3 DPG, low PaO2

29
Q

Relationship of SpO2 and PaO2 with a rightward shift of the OHDC

A

SpO2 decreases, PaO2 increases

30
Q

Relationship of SpO2 and PaO2 with a leftward shift of the OHDC

A

SpO2 increases, PaO2 decreases

31
Q
A