Rosh (1/10) Flashcards
Syphilis stages
Primary: painless chancre
Secondary: lymphadenopathy, condyloma lata, rash on palms/soles
Syphilis treatment
Penicillin G IM x 1 dose for primary or secondary
x 3 doses, weekly for tertiary
VDRL or RPR become positive…
1-4 wks after infection
False positive syphilis abs in patients with
Lupus or Lyme disease
Evidence of successful syphilis treatment
Nontreponeal titers drop 4-fold in 1 year
Antibodies will be positive to suggest history of infection
Guideline for cholesterol screening
Screen at 45 y/o unless risk factors (then 30-35 y/o), then q5yrs if no therapy or q3yrs if therapy
Bile acid sequestrants
Cholestyramine
Reduce LDL, do not affect TG
Statins
Reduce LDL, increase HDL
Fibric acids
Fenofibrate Reduce TG (if very high, over 500) and LDL
Niacin
Reduce TG (if very high), increase HDL Many side effects including flushing, pruritis, and nausea
Amount of fluids for sepsis
30 mL/kg for hypotension or lactate of 4
DiGeorge syndrome
Cardiac abnormalities (often ToF) Abnormal facies Thymic absence / T cell abnormality Cleft palate Hypocalcemia 22 chromosome
Tetralogy of Fallot
Pulmonary stenosis
Overriding aorta
VSD
RVH (after birth)
Congenital rubella defect
PDA or branch pulmonic stenosis
Apical displacement of tricuspid valve
Ebstein anomaly
Lithium exposure
Turner syndrome heart defect
Coarcation of aorta or aortic stenosis
Nerve controlling external anal spincter
Pudendal
Tamiflu dosing for flu exposure ppx in pregnancy
75 mg qd x 7d
Diagnosis of APLS
Antibodies twice 12 weeks apart +
Death of a morphologically normal infant >10 wga
OR thromboembolic disease
OR 3 or more consecutive miscarriages
OR birth earlier than 34 wga for sPEC or placental insufficiency
Osteoporosis
T score less than or equal to -2.5
also start therapy if risk of hip fracture >3% or risk of any fracture >20%
Medical therapy for weight loss
Orlistat, decreases fat absorption, can cause flatulence and fatty stools
Johnson Maneuver
replacement of uterus manually after inversion
Haultain Procedure
laparotomy with incision in posterior aspect of uterus to allow for reduction of inversion
Huntington Procedure
laparotomy with clamps used to pull uterus out of inversion
Treatment for CMV
Ganciclovir
CMV avidity meaning
High avidity means old infection
Trastuzumab use
Treat HER2/neu + breast cancer
Tamoxifen use in breast cancer
ER and/or PR + treatment in pre- or post-menopausal
increased endometrial cancer risk
Raloxifene use
Treats low bone density
Anastrozole use in breast cancer
Treat ER/PR+ breast cancer, mostly in postmenopausal women
Fragile X genetics
FMR1 gene premutation (55-200 repeats)
Low lying placenta
Less than 2 cm from the os
Gaskin maneuver
Hands and knees for shoulder
Pinares maneuver
Delivery of legs in beech vaginal
Loveset
Delivery of arms in breech vaginal